Rifampicin (RIF) is a benchmark drug for treatment of tuberculosis, but poor bioavailability, prolonged treatment, and pill burden have been linked to therapeutic failure and the development of multidrug resistant strains. To overcome these limitations, this study investigated a method of rifampicin nanoencapsulation and aerosol delivery using a commercial, hand-held nebulizer modified with a nitrogen stream.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792303PMC
http://dx.doi.org/10.1039/C5RA25044GDOI Listing

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