Introduction: The objective of this study was to assess whether the nascent, but rapidly growing e-liquid industry prohibits Internet sales to minors and employs safety measures to prevent accidental poisonings.
Methods: A stratified simple random sample (n = 120) was selected from the target population (N = 1107) of US online vendors of e-liquid in July 2015. The vendors were stratified and subsequently oversampled by trade association membership and vendor popularity. Three minors aged 16 to 17, who were supervised by adult research staff, attempted to purchase e-liquid from the 120 online vendors using debit cards issued in their names. Measures included vendors' use of age verification, warning labels on e-liquid bottles, and child-resistant packaging.
Results: Statistically significant differences were observed by vendor popularity, but not by membership in a trade association. The differences by vendor popularity, however, occurred for measures that were limited to an age warning and list of ingredients. The most striking finding was the scant vendors (n = 4) who successfully prevented the sale of e-liquid to the minors. In contrast, 87.5% and 53.9% of the bottles contained child-resistant packaging and a health warning label, respectively.
Conclusions: Irrespective of trade association membership or vendor popularity, online vendors of e-liquids are not taking the proper precautions in preventing sales to minors. The FDA's upcoming deeming rules on e-cigarette products should include explicit requirements for offline and online e-liquid vendors, particularly the use of effective age verification, warning labels, and child-resistant packaging.
Implications: This study demonstrates that, in the absence of any current FDA regulation of e-liquid products, self-regulation among vendors is not effective in preventing product acquisition by minors. Lax oversight of the e-liquid industry may draw consumers to bypass current tobacco control restrictions implemented in face-to-face sales settings. As a consequence, there may be an increase in online sales to minors. Further regulation of the industry may increase the already prevalent use of child-resistant packaging, leading to fewer cases of accidental nicotine poisoning.
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http://dx.doi.org/10.1093/ntr/ntw091 | DOI Listing |
PLoS One
January 2025
School of Statistics and Mathematics, Yunnan University of Finance and Economics, Kunming, Yunnan, China.
With the popularity of circular economy around the world, transactions in the second-hand sailboat market are extremely active. Determining pricing strategies and exploring their regional effects is a blank area of existing research and has important practical and statistical significance. Therefore, this article uses the random forest model and XGBoost algorithm to identify core price indicators, and uses an innovative rolling NAR dynamic neural network model to simulate and predict second-hand sailboat price data.
View Article and Find Full Text PDFPLoS One
January 2025
School of Management, Foshan University, Foshan, China.
Entrepreneurship is an increasingly popular career choice among students, driven by the transformative impact of emerging technologies and evolving professional landscapes. This study focuses on how higher education shapes students' professional identities and entrepreneurial intentions, particularly among business school students. Utilizing the Theory of Planned Behavior (TPB) as the foundational framework, the study examines the factors influencing entrepreneurial intentions, with a specific emphasis on the moderating role of departmental identification.
View Article and Find Full Text PDFJ Hist Dent
January 2025
Clinic Director, Cavity Busters Doylestown, Doylestown, PA Adjunct Professor Pediatric Dentistry University of Texas HSC at San Antonio Clinical Professor, Pediatric Dentistry Case Western Reserve School of Dental Medicine.
A unique type of advertising trade card was popular in Europe, mostly Belgium, between 1840 and 1865. These cards were produced with a coating of a white lead substance that gave them a lustrous appearance and feel, resembling porcelain. As attractive as these cards were, producing them oftentimes resulted in lead poisoning for the printers, so few were produced after 1865.
View Article and Find Full Text PDFNMR Biomed
February 2025
Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
The need to quantify brain glutathione (GSH) accurately by J-difference spectroscopy has stimulated assessment of the TE effects on GSH edited signals at the popular field strength 3 T. We performed multiple-TE J-difference MRS at two sites to evaluate the GSH T relaxation and TE dependence of the GSH signal resolution. Two 10-ms spectrally selective Gaussian editing RF pulses were implemented in 3 T MEGA-PRESS sequences at two sites having different vendors.
View Article and Find Full Text PDFJMIR Form Res
December 2024
REACH Lab, Department of Pediatrics, Division of Adolescent Medicine, Stanford University, Palo Alto, CA, United States.
Background: Electronic cigarettes (e-cigarettes) are the most used form of tobacco products among adolescents and young adults, and Vuse is one of the most popular brands of e-cigarettes among US adolescents. In October 2021, Vuse Solo became the first e-cigarette brand to receive marketing granted orders (MGOs) from the US Food and Drug Administration (FDA), authorizing its marketing and their tobacco-flavored pods. Vuse Ciro and Vuse Vibe, and their tobacco-only ("original") e-liquids, were authorized for marketing in May 2022 and Vuse Alto tobacco-flavored devices were authorized in July 2024.
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