AI Article Synopsis
- The traditional processes of membranous and endochondral ossification do not fully account for all the characteristics of the developing skeleton, especially regarding the role of chondroid tissue.
- Researchers have identified chondroid tissue in various regions, including the mandibular symphysis of human and cat fetuses, as well as in other areas of the mandible, skull sutures, and all bones in both the axial and appendicular skeleton.
- The formation of chondroid tissue from mesenchyme may be influenced by mechanical forces acting in reverse directions or periods of temporary reduced blood flow (ischemia).
Article Abstract
Membranous and endochondral ossification processes are insufficient to describe all the aspects observed in the growing skeleton. The presence of chondroid tissue that we have identified by means of all modern histological techniques, including those able to detect the different types of collagen, has also to be explained. Present in the mandibular symphysis of either the human or cat fetuses, chondroid tissue has also been observed in the other parts of the mandible, in the sutural areas of the skull and in all the bones of both axial and appendicular skeleton. The differentiation of the mesenchyme into chondroid tissue could probably be related with mechanical forces exerted simultaneously in opposite directions or with a transient ischemia.
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