ISOL-8: A Multicenter, Retrospective Study of the Effectiveness of the Trellis-8 to Treat Iliofemoral DVT and Prevent Post-thrombotic Syndrome.

J Vasc Surg Venous Lymphat Disord

Southern Ohio Surgical Associates, Portsmouth, Ohio.

Published: January 2013

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http://dx.doi.org/10.1016/j.jvsv.2012.10.031DOI Listing

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Background: Deep vein thrombosis (DVT) occurs in up to 600,000 patients in the United States annually and can lead to long-term morbidity because of the post-thrombotic syndrome. The multicenter isolated-pharmacomechanical thrombolysis device (ISOL-8) study was designed to determine the safety and efficacy of the Trellis™-8 peripheral infusion system when used as the primary intervention to achieve DVT thrombolysis in patients with proximal lower-extremity occlusive DVT, and track the incidence and severity of the post-thrombotic syndrome (PTS) symptoms in patients 2 years after treatment.

Methods: Data were collected retrospectively from 6 centers on patients treated with the Trellis-8 system, an isolated-pharmacomechanical thrombolysis device (IPMTD).

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