A novel homogeneous polysaccharide fraction (APS) was extracted from Astragalus by hot water and purified by Sephadex G-100 and G-75 column. Its molecular weight was 693kDa. APS and APS with ultra-high pressure treatment exhibited significant inhibitory abilities on a-glucosidase, inhibition rate from high to low in order was 400MPa-APS, 300MPa-APS, 500MPa-APS and APS. The inhibition percentage of 400MPa-APS (1.5mg/mL) was 49% (max.). This suggested that the inhibitory activity of APS on a-glucosidase was improved by ultra-high pressure treatment. FT-IR, SEM, CD spectra, atomic force microscope and Congo red test analysis of APS and 400MPa-APS showed ultra-high pressure treatment didn't change the preliminary structure but had an effect on its advanced structure.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ijbiomac.2016.03.024 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Growth of MoS Nanosheets on Brush-Shaped PI-ZnO Hybrid Nanofibers and Study of the Photocatalytic Performance.
Nanomaterials (Basel)
December 2024
College of Materials Science and Engineering, Jiangsu University of Science and Technology, Zhenjiang 212003, China.
The design and preparation of advanced hybrid nanofibers with controllable microstructures will be interesting because of their potential high-efficiency applications in the environmental and energy domains. In this paper, a simple and efficient strategy was developed for preparing hybrid nanofibers of zinc oxide-molybdenum disulfide (ZnO-MoS) grown on polyimide (PI) nanofibers by combining electrospinning, a high-pressure hydrothermal process, and in situ growth. Unlike simple composite nanoparticles, the structure is shown in PI-ZnO to be like the skeleton of a tree for the growth of MoS "leaves" as macro-materials with controlled microstructures.
View Article and Find Full Text PDFSystematic Characterization of the Chemical Constituents of in Vitro and in Vivo of Astragali Radix-Salvia miltiorrhiza Herb Pair by Ultra-High-Performance-Liquid Chromatography-Orbitrap Mass Spectrometry.
Rapid Commun Mass Spectrom
April 2025
School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Rationale: Astragali radix-Salvia miltiorrhiza (AR-SM) is an herb pair with good therapeutic effects and is widely used. In this study, the in vitro and in vivo components of AR-SM were quickly classified and identified based on UHPLC-orbital mass spectrometry. This provided a basis for clarifying the bioactive substances after compatibility of AR and SM.
View Article and Find Full Text PDFHybrid coating prepared with PMMA/Ti-O-Si tested under vacuum conditions for use in nanosatellites.
PLoS One
January 2025
Departamento de Reología y Mecánica de Materiales, Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México Ciudad Universitaria, Ciudad de México, México.
A hybrid coating made of poly (methyl methacrylate) with SiO2-TiO2 particles (PMMA/SiO2-TiO2) has been developed for use as a coating on nanosatellites, evaluating its resistance to high vacuum by quantifying its weight loss. The coating was applied on an Al 7075 aluminum substrate used for the aerospace sector. PMMA/SiO2-TiO2 hybrid coatings were prepared using sol-gel reaction in situ assisted with sonochemistry.
View Article and Find Full Text PDFPerfluorinated compounds linked to central precocious puberty in girls during COVID-19: an untargeted metabolomics study.
Front Endocrinol (Lausanne)
January 2025
Department of Pediatrics, Hainan Medical University School of Pediatrics, Hainan Women and Children's Medical Center, Haikou, Hainan, China.
Background And Objective: The incidence of central precocious puberty (CPP) in girls increased significantly during the COVID-19 pandemic. This study aimed to explore the impact of perfluorinated endocrine disruptors on CPP through metabolomics analysis in girls from Hainan Province, China.
Methods: Serum samples from 100 girls with CPP and 100 healthy controls were collected.
Important Aspects of the Design of Experiments and Data Treatment in the Analytical Quality by Design Framework for Chromatographic Method Development.
Molecules
December 2024
Institute of Chemistry, University of Campinas (UNICAMP), Campinas 13083-970, SP, Brazil.
In the analytical quality by design (AQbD) framework, the design of experiments (DOE) plays a very important role, as it provides information about how experimental input variables influence critical method attributes. Based on the information obtained from the DOE, mathematical models are generated and used to build the method operable design region (MODR), which is a robust region of operability. Data treatment steps are usually carried out in software such as Fusion QbD, Minitab, or StaEase 360, among others.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!