J Vasc Surg Venous Lymphat Disord
Center for Vascular Diagnostics, Division of Vascular Surgery, the University of Maryland School of Medicine, Baltimore, Md; Veterans Affairs Medical Center, Baltimore, Md. Electronic address:
Published: April 2013
Objective: Sequential compression devices or ambulation prevent deep venous thrombosis (DVT) by enhancing venous blood flow in the lower extremity. However, compression therapy or ambulation may not be possible in patients with lower extremity surgery or trauma. We therefore determined whether upper body exercise increases venous blood flow in the lower extremities as a potential means for preventing DVT.
Methods: We determined blood volume flow and velocity responses in the common femoral veins to low-intensity (5 W, 75 rpm) upper body cycle ergometry in healthy individuals. Six protocols of single and intermittent bouts of exercise were tested. Upon determination of the most efficacious protocol in these participants, we verified the effects of upper body exercise in patients with acute DVT. Measurements were made before, during, and after exercise using duplex ultrasound imaging.
Results: The study enrolled 15 healthy volunteers (10 men, 5 women; aged 20-40 years) with no history of DVT and 10 patients (aged 31-86 years) with acute DVT. In healthy participants, a single 30-second bout of upper body exercise increased volume flow up to 39% for up to 10 minutes after exercise (P < .05). A single 3-minute bout increased flow to a lesser extent (23% increase; P = .05) for nearly 5 minutes, but a single 1-minute bout did not increase flow. An intermittent protocol of three 30-second bouts of exercise resulted in an increase of 34% to 57% in venous flow (P < .05) for an average increase of 179 ± 53 mL/min. Intermittent 1-minute bouts of exercise tended to increase flow 10% to 40% (P = .06-.08) for an average increase of 149 ± 64 mL/min. Intermittent 3-minute bouts of exercise increased flow 21% to 45% (P < .05) for an average increase of 120 ± 42 mL/min. In patients with acute DVT, the intermittent 30-second upper body exercise protocol increased venous blood flow by 45% to 83% (P < .05) for an average increase of 250 ± 63 mL/min, an effect lasting >13 minutes.
Conclusions: We report the novel finding that upper body exercise increases lower extremity venous blood flow in healthy volunteers and in acute DVT patients. Three intermittent 30-second bouts of low-intensity upper body exercise elicited the highest response for the least amount of effort and may represent an alternative or adjunct for prophylaxis of DVT in patients with restricted ambulation.
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Sci Rep
January 2025
Biomedical Research Center, Qatar University, P.O Box 2713, Doha, Qatar.
Regular aerobic exercise has a significant impact on glucose metabolism and lipid profiles, contributing to overall health improvement. However, evidence for optimal exercise duration to achieve these effects is limited. This study aims to explore the effects of 4 and 8 weeks of moderate-intensity aerobic exercise on glucose metabolism, lipid profiles, and associated metabolic changes in young female students with insulin resistance and varying body mass, seeking to determine the optimal duration for physiological adaptations.
View Article and Find Full Text PDFSkeletal Radiol
January 2025
Department of Radiology, Fukui Prefectural Hospital, 2-8-1 Yotsui, Fukui City, 910-8526, Japan.
Objectives: Paravertebral crystal deposition disease, characterized by the deposition of crystals around the vertebral bodies leading to acute inflammation and pain, is a condition that remains largely unrecognized. This study aims to elucidate the prevalence, clinical features, and CT findings associated with this disease.
Methods: We retrospectively analyzed 14,839 consecutive patients who underwent chest and/or abdominal CT (September 2017 to September 2024) owing to chest, abdominal, or back pain.
Ann Oncol
January 2025
Division of Surgical Oncology, Department of Surgery, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.
Purpose: To assess the association between neoadjuvant therapy and overall survival (OS) in patients with left-sided resectable pancreatic cancer (RPC) compared to upfront surgery.
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Pathol Res Pract
January 2025
Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, Shandong 262000, PR China. Electronic address:
Gastric duplication cysts (GDCs) are rare cystic neoplasms that are often difficult to distinguish from other entities. Accurate diagnosis of cysts before resection is difficult even using the most advanced imaging techniques. We present a case of a gastric duplication cyst in a 17-year-old female, presenting with discomfort in the upper abdomen.
View Article and Find Full Text PDFJ Appl Stat
May 2024
Department of Mathematics, Brunel University London, Uxbridge, UK.
Although the fractional polynomials (FPs) can act as a concise and accurate formula for examining smooth relationships between response and predictors, modelling conditional mean functions observes the partial view of a distribution of response variable, as distributions of many response variables such as blood pressure (BP) measures are typically skew. Conditional quantile functions with FPs provide a comprehensive relationship between the response variable and its predictors, such as median and extremely high-BP measures that may be often required in practical data analysis generally. To the best of our knowledge, this is new in the literature.
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