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The sphingosine-1-phosphate signaling pathway (sphingosine-1-phosphate and its receptor, sphingosine kinase) and epilepsy.
Epilepsia Open
December 2024
Department of Oncology, Affiliated Hospital of Jining Medical University, Jining City, China.
Epilepsy is one of the common chronic neurological diseases, affecting more than 70 million people worldwide. The brains of people with epilepsy exhibit a pathological and persistent propensity for recurrent seizures. Epilepsy often coexists with cardiovascular disease, cognitive dysfunction, depression, etc.
View Article and Find Full Text PDFAmplitude modulation structure in French and German poetry: universal acoustic physical structures underpin different poetic rhythm structures.
R Soc Open Sci
September 2024
Centre for Neuroscience in Education, University of Cambridge, Cambridge, UK.
French and German poetry are classically considered to utilize fundamentally different linguistic structures to create rhythmic regularity. Their metrical rhythm structures are considered poetically to be very different. However, the biophysical and neurophysiological constraints upon the speakers of these poems are highly similar.
View Article and Find Full Text PDFThe role of deep layer superior colliculus neurons in prepulse inhibition and the impact of spatial separation in male rats.
Neuroscience
December 2024
School of Psychological and Cognitive Sciences, Peking University, Beijing 100080, China.
Prepulse inhibition (PPI) refers to the phenomenon in which a weak sensory stimulus before a strong one significantly reduces the startle reflex caused by the strong stimulus. Perceptual spatial separation, a phenomenon where auditory cues from the prepulse and background noise are distinguished in space, has been shown to enhance PPI. This study aims to investigate the neural modulation mechanisms of PPI by the spatial separation between the prepulse stimulus and background noise, particularly in the deep superior colliculus (deepSC).
View Article and Find Full Text PDFSemantic Integration Demands Modulate Large-Scale Network Interactions in the Brain.
Hum Brain Mapp
December 2024
Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
The ability to integrate semantic information into the context of a sentence is essential for human communication. Several studies have shown that the predictability of a final keyword based on the sentence context influences semantic integration on the behavioral, neurophysiological, and neural level. However, the architecture of the underlying network interactions for semantic integration across the lifespan remains unclear.
View Article and Find Full Text PDFThe power of sound: Exploring the auditory influence on visual search efficiency.
Cognition
December 2024
School of Psychology, Liaoning Collaborative Innovation Center of Children and Adolescents Healthy Personality Assessment and Cultivation, Liaoning Normal University, Dalian 116029, China; School of Foreign Languages, Ningbo University of Technology, Ningbo 315211, China. Electronic address:
In a dynamic visual search environment, a synchronous and meaningless auditory signal (pip) that corresponds with a change in a visual target promotes the efficiency of visual search (pop out), which is known as the pip-and-pop effect. We conducted three experiments to investigate the mechanism of the pip-and-pop effect. Using the eye movement technique, we manipulated the interval rhythm (Exp.
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