Cyclosporine-induced sebaceous hyperplasia (SH) is a well-documented entity, occurring in up to 30% of renal transplant patients treated with cyclosporine and has also been reported to occur following heart or hematopoetic stem cell transplantation (HCST). Cyclosporine has a stimulatory effect on undifferentiated sebocytes, resulting in the clinical and histologic findings in these patients. Sebaceous hyperplasia most commonly presents as asymptomatic papules over the face, chest, or groin. Herein we describe a case of a 27-year-old man who developed facial sebaceous hyperplasia five months after completing cyclosporine therapy for cutaneous graft versus host disease (GVHD) following HSCT.

Download full-text PDF

Source

Publication Analysis

Top Keywords

sebaceous hyperplasia
16
cyclosporine-induced sebaceous
8
hematopoetic stem
8
stem cell
8
hyperplasia
4
hyperplasia hematopoetic
4
cell transplant
4
transplant patient
4
patient delayed
4
delayed onset
4

Similar Publications

Skin Barrier Dysfunction in Acne Vulgaris: Pathogenesis and Therapeutic Approaches.

Med Sci Monit

December 2024

Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Yunnan Provincial Dermatology Hospital, Kunming, Yunnan, China.

Acne vulgaris is a chronic inflammatory disease of the hair follicle-sebaceous gland unit and is the most common skin disorder worldwide. Although it can occur at any age, it predominantly affects young individuals, manifesting as comedones, papules, pustules, cysts, and nodules, primarily in the sebaceous-rich areas of the face, often in a symmetrical distribution. The development of acne vulgaris is believed to result from a combination of genetic and environmental factors, including sun exposure, skincare habits, diet, sleep patterns, and psychological stress, all of which can induce or exacerbate the condition.

View Article and Find Full Text PDF

Sebaceous gland hyperplasia is a benign cutaneous entity commonly seen in older men. Occasionally, it can develop in young patients on immunosuppression with cyclosporine or in adolescent boys in the peripubertal age group. It is extremely rare in young children with no reports of eyelid involvement.

View Article and Find Full Text PDF

Sebaceous Hyperplasia of the Face: A Case Report.

Cureus

October 2024

Oral and Maxillofacial Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.

Sebaceous hyperplasia is a benign condition characterized by an overgrowth of sebaceous glands, often presenting as small, soft, yellowish papules on areas rich in sebaceous glands, such as the face. While the condition is harmless, it can mimic other dermatological conditions, such as basal cell carcinoma. This case report describes a 71-year-old female with sebaceous hyperplasia presenting as wart-like lesions and whiteheads on the forehead and cheek regions.

View Article and Find Full Text PDF
Article Synopsis
  • This study compares cryotherapy and electrosurgery methods for removing bothersome skin conditions like sebaceous hyperplasia and cherry angioma.
  • Conducted as an assessor-blind trial with 32 lesions in each treatment group, it assessed patient and physician satisfaction over several follow-up visits.
  • Results indicated that while electrosurgery showed higher satisfaction for most conditions, cryotherapy was more effective for treating seborrheic keratosis; some side effects like hypopigmentation were observed in both methods.
View Article and Find Full Text PDF
Article Synopsis
  • Distinguishing between benign and potentially malignant skin tumors is crucial in family medicine, and many benign tumors can be diagnosed based on their history, appearance, and growth patterns.
  • Procedures like biopsy or excision may be necessary if there's uncertainty about a diagnosis or if the lesion changes rapidly.
  • Treatment options vary based on the type of lesion and patient preference, with methods like excision, laser therapy, and cryotherapy commonly used; special considerations are needed for patients with darker skin to minimize risks like hypopigmentation.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!