Cyclosporine-induced sebaceous hyperplasia (SH) is a well-documented entity, occurring in up to 30% of renal transplant patients treated with cyclosporine and has also been reported to occur following heart or hematopoetic stem cell transplantation (HCST). Cyclosporine has a stimulatory effect on undifferentiated sebocytes, resulting in the clinical and histologic findings in these patients. Sebaceous hyperplasia most commonly presents as asymptomatic papules over the face, chest, or groin. Herein we describe a case of a 27-year-old man who developed facial sebaceous hyperplasia five months after completing cyclosporine therapy for cutaneous graft versus host disease (GVHD) following HSCT.
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Med Sci Monit
December 2024
Department of Dermatology, First Affiliated Hospital of Kunming Medical University, Yunnan Provincial Dermatology Hospital, Kunming, Yunnan, China.
Acne vulgaris is a chronic inflammatory disease of the hair follicle-sebaceous gland unit and is the most common skin disorder worldwide. Although it can occur at any age, it predominantly affects young individuals, manifesting as comedones, papules, pustules, cysts, and nodules, primarily in the sebaceous-rich areas of the face, often in a symmetrical distribution. The development of acne vulgaris is believed to result from a combination of genetic and environmental factors, including sun exposure, skincare habits, diet, sleep patterns, and psychological stress, all of which can induce or exacerbate the condition.
View Article and Find Full Text PDFSebaceous gland hyperplasia is a benign cutaneous entity commonly seen in older men. Occasionally, it can develop in young patients on immunosuppression with cyclosporine or in adolescent boys in the peripubertal age group. It is extremely rare in young children with no reports of eyelid involvement.
View Article and Find Full Text PDFCureus
October 2024
Oral and Maxillofacial Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Sebaceous hyperplasia is a benign condition characterized by an overgrowth of sebaceous glands, often presenting as small, soft, yellowish papules on areas rich in sebaceous glands, such as the face. While the condition is harmless, it can mimic other dermatological conditions, such as basal cell carcinoma. This case report describes a 71-year-old female with sebaceous hyperplasia presenting as wart-like lesions and whiteheads on the forehead and cheek regions.
View Article and Find Full Text PDFHealth Sci Rep
November 2024
Department of Dermatology Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine Iran University of Medical Sciences Tehran Iran.
Am Fam Physician
October 2024
Prisma Health and the University of South Carolina School of Medicine, Greenville.
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