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Mean Differences for 3 Delivery Modalities of the Healthy Eating, Staying Active As We Age Curriculum for Older Adults.
J Nutr Educ Behav
January 2025
Virginia Cooperative Extension Family Nutrition Program, Virginia Tech, Blacksburg, VA; Department of Human Nutrition, Foods, and Exercise, Virginia Tech, Blacksburg, VA.
Objective: To assess the mean differences in outcomes of 3 delivery modalities of a nutrition education program targeting older adults.
Methods: A natural experiment was conducted from March 2020 to September 2021, with presurveys and postsurveys used to assess dietary and physical activity behaviors. Results were analyzed using descriptive statistics, t tests, and ANOVA, with a Bonferroni-corrected significance threshold at P < 0.
The Management of Upper-Extremity Xylazine-Associated Wounds.
J Hand Surg Am
January 2025
Cooper University Hospital, Camden, NJ.
Purpose: Xylazine has been associated with necrotic soft tissue wounds that have placed a challenging burden on patients who inject drugs in the Philadelphia region's health care system over the last few years. An analysis of our initial experience is being presented to guide future treatment and directions for future research.
Methods: A retrospective review of 55 patients with patient-reported xylazine use and associated upper-extremity wounds at a single institution was performed.
Protein prenylation in mechanotransduction: implications for disease and therapy.
Trends Pharmacol Sci
January 2025
Department of Cardiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. Electronic address:
The process by which cells translate external mechanical cues into intracellular biochemical signals involves intricate mechanisms that remain unclear. In recent years, research into post-translational modifications (PTMs) has offered valuable insights into this field, spotlighting protein prenylation as a crucial mechanism in cellular mechanotransduction and various human diseases. Protein prenylation, which involves the covalent attachment of isoprenoid groups to specific substrate proteins, profoundly affects the functions of key mechanotransduction proteins such as Rho, Ras, and lamins.
View Article and Find Full Text PDFNavigating "regulatory fog": Challenges to rigorous abortion research after the Dobbs v. Jackson decision.
Contraception
January 2025
Collaborative for Reproductive Equity, Department of Obstetrics and Gynecology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, 1300 University Avenue, Medical Sciences Center 4245 Madison, WI 53706 USA. Electronic address:
In 2022, the United States' Supreme Court ruling in Dobbs v. Jackson Women's Health Organization overturned Roe v. Wade and federal protections for abortion.
View Article and Find Full Text PDFAssociation between exposure to pyrethroids and chlorpyrifos at age 5 years and IQ at age 7 years among children from the Odense Child Cohort, a prospective birth cohort study.
Environ Res
January 2025
Department of Clinical Pharmacology, Pharmacy and Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark; Hans Christian Andersen Children's Hospital, Odense University Hospital, Odense, Denmark; OPEN Patient Data Explorative Network, Odense, Denmark.
Background: Over the past decade, the use of organophosphate insecticides including chlorpyrifos has faced increasing restrictions due to health concerns, leading to a rise in use of pyrethroids. Concerns about neurodevelopmental insults following pyrethroids exposure exist, but few studies have examined the long-term effects of childhood exposure to chlorpyrifos and pyrethroids on IQ.
Objective: To investigate the prospective associations between pyrethroids and chlorpyrifos exposure at age 5 years and IQ scores assessed at age 7.
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