AI Article Synopsis
- Hemiscrotal agenesis is a very rare condition with only three documented cases, making its clinical features not well understood.
- A reported case involved hemiscrotal agenesis alongside ipsilateral cryptorchidism; treatment included scrotoplasty and orchiopexy, which helped enhance the thermal environment for the remaining testis.
- Low expression of certain androgen-related genes on the affected side likely contributed to the absence of normal scrotal features, suggesting that scrotoplasty may be a viable option for managing hemiscrotal agenesis and its impact on future fertility.
Article Abstract
Hemiscrotal agenesis is among the rarest anomalies in scrotal development disorders. As it has only been reported in three cases, the clinical manifestations remain unclear. We report a case of hemiscrotal agenesis with ipsilateral cryptorchidism. Based on the thermal assessment of the scrotum, concurrent scrotoplasty and orchiopexy were carried out, and the scrotoplasty improved the thermal environment of the fixed left testis. Furthermore, the low expression of androgen receptor and steroid-5-alpha-reductase, alpha polypeptide 2 in the affected side of the scrotum likely resulted in the characteristics of absent scrotal rugae, and pigmentation on histological and biological analyses. For future fertility, we believe that scrotoplasty should be considered as a management option for hemiscrotal agenesis.
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| http://dx.doi.org/10.1111/iju.13079 | DOI Listing |
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