Nano-biomaterials for cardiovascular applications: Clinical perspective.

J Control Release

Cardiovascular Nanomedicine Unit, Section of Experimental Oncology and Nanomedicine, ENT-Department, University Hospital Erlangen, Germany.

Published: May 2016

AI Article Synopsis

  • Cardiovascular diseases, such as ischemic heart disease and stroke, account for nearly 25% of global deaths, and their rates are rising despite advancements in medical diagnostics and treatments.
  • Biomaterials, particularly in nanoformulations, offer numerous advantages over synthetic options, including improved biocompatibility and effectiveness as drug carriers or protective agents.
  • This review highlights significant scientific reports on (nano)biomaterials, focusing on enhancing existing solutions and creating new constructs for cardiovascular applications.

Article Abstract

Cardiovascular diseases, including ischemic heart disease and stroke, are responsible for nearly 25% of all deaths worldwide. Globally, their prevalence continues to increase, in spite of enormous progress in cardiovascular diagnostics and therapy. For therapeutic and regenerative purposes, biomaterials promise solutions with multiple advantages over synthetic materials. Furthermore, their easy availability as nanoformulations recommends their application as drug carriers or protective nanoshells improving the biocompatibility of imaging agents. In this work, we review the most promising and clinically meaningful scientific reports with regard to (nano)biomaterials with particular focus on potential improvements of existing, and development of novel constructs for cardiovascular applications.

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Source
http://dx.doi.org/10.1016/j.jconrel.2016.03.015DOI Listing

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