Background: The incidence of health care-acquired infection (HAI) and the consequence for patients with HAI tend to vary from study to study. By including all patients, all medical specialties, and performing a follow-up analysis, this study contributes to previous findings in this research field.
Methods: Data from the Swedish National Point Prevalence Surveys of HAI 2010-2012 was merged with cost per patient data from the county Health Care Register (N = 6,823). Extended length of stay (LOS) and costs related to an HAI were adjusted for sex, age, intensive care unit use, and surgery.
Results: Patients with HAI (n = 732) had a larger proportion of readmissions compared with patients with no HAI (29.0% vs 16.5%). Of the total bed days, 9.3% was considered to be excess days attributed to the group of patients with an HAI. The excess LOS comprised 11.4% of the total costs (95% CI, 10.2-12.7). The 1-year overall mortality rate for patients with HAI in comparison to all other patients was 1.75 (95% CI, 1.45-2.11), all 5 of these differences were statistically significant (P < .001).
Conclusions: Even if not all outcomes for patients with an HAI can be explained by the HAI itself, the increase in inpatient days, readmissions, associated costs, and higher mortality rates are quite notable.
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http://dx.doi.org/10.1016/j.ajic.2016.01.035 | DOI Listing |
Metabolism
January 2025
State Key Laboratory for Innovation and Transformation of Luobing Theory, Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China. Electronic address:
Aims: Obesity, as a worldwide healthcare problem, has become more prevalent. ZFP36 is a well-known RNA-binding protein and involved in the posttranscriptional regulation of many physiological processes. Whether the adipose ZFP36 plays a role in obesity and insulin resistance remains unclear.
View Article and Find Full Text PDFCureus
December 2024
Department of Gastroenterology, Scripps Mercy Hospital, San Diego, USA.
Hemosuccus pancreaticus (HP) is a rare, life-threatening cause of upper gastrointestinal bleeding, often linked to chronic pancreatitis and pseudoaneurysm rupture into the pancreatic duct. However, its occurrence in acute necrotizing pancreatitis with decompensated cirrhosis is exceedingly rare and poses significant diagnostic and treatment challenges. We report a case of a 34-year-old male with decompensated alcoholic cirrhosis who developed hemorrhagic shock from HP following acute necrotizing pancreatitis.
View Article and Find Full Text PDFCureus
December 2024
Department of Occupational Therapy, Faculty of Rehabilitation, Niigata University of Health and Welfare, Niigata, JPN.
Transcranial magnetic stimulation (TMS) is an effective intervention for improving cognitive impairment in patients with stroke. However, its effectiveness in the subdomains of cognition is conflicting and not clearly established. This systematic review assessed the efficacy of TMS in improving executive function, attention, and memory in this population.
View Article and Find Full Text PDFInfect Prev Pract
March 2025
Department of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
Introduction: Hospital-acquired infections (HAIs) present a global public health challenge, impacting patient safety and incurring substantial economic costs across healthcare settings. This study aims to accurately measure the financial burden of HAIs by analyzing real costs associated with various infections, providing insights for targeted prevention and management strategies.
Methods: This retrospective cohort study at a university hospital in Rome, Italy, analysed Hospital Discharge Records (HDR) from January to December 2018, focusing on patients with and without HAIs.
Cell Mol Gastroenterol Hepatol
January 2025
Division of Biomedical Sciences, School of Medicine, University of California Riverside, Riverside, California, USA. Electronic address:
Background: Coronavirus disease (COVID-19), caused by SARS-CoV-2, triggered a global pandemic with severe medical and socioeconomic consequences. While fatality rates are higher among the elderly and those with underlying comorbidities, host factors that promote susceptibility to SARS-CoV-2 infection and severe disease are poorly understood. Although individuals with certain autoimmune/inflammatory disorders show increased susceptibility to viral infections, there is incomplete knowledge of SARS-CoV-2 susceptibility in these diseases.
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