Macrolide-resistant Mycoplasma pneumoniae plays an important role in refractory M. pneumoniae pneumonia. Here, we present the whole-genome sequencing of the macrolide-resistant M. pneumoniae strain S355. The annotated full-genome sequence might provide a new insight into drug resistance in M. pneumoniae and can help pediatricians recognize the disease earlier.
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http://dx.doi.org/10.1128/genomeA.00087-16 | DOI Listing |
China CDC Wkly
January 2025
Department of Clinical Laboratory, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, China.
Introduction: Type F () represents a significant pathogen in human gastrointestinal diseases, primarily through its gene encoding enterotoxin (CPE). This investigation examined the prevalence, antimicrobial resistance patterns, and genetic characteristics of Type F within the Chinese population.
Methods: The study analyzed 2,068 stool samples collected from 11 provincial hospitals in 2024.
Pak J Med Sci
January 2025
Lamei Yuan, MD, PhD, Health Management Center, the Third Xiangya Hospital, Disease Genome Research Center, Center for Experimental Medicine, the Third Xiangya Hospital, Research Center of Medical Experimental Technology, the Third Xiangya Hospital, Xiangya School of Medicine, Central South University, Changsha 410013, Hunan, China.
Objective: To identify the disease-causing variant in a family with tuberous sclerosis complex (TSC).
Methods: This study including a Han-Chinese pedigree recruited from the Third Xiangya Hospital, Central South University, Changsha, Hunan, China was conducted between February, 2019 and January, 2023. Detailed clinical examinations were performed on the proband and other family members of a Han-Chinese family with TSC.
Insecta mundi
December 2023
Departments of Biophysics and Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9050 USA.
A century and a half since the time of Hewitson, we are experiencing a renaissance in species discovery fueled by whole genome sequencing. A large-scale genomic analysis of Hesperiidae Latreille, 1809 (Lepidoptera), including primary type specimens, reveals a deluge of species new to science. One hundred of them (one in a new genus) are described here from the New World (type localities are given in parenthesis): () Grishin, (Ecuador: Napo), Grishin, (Ecuador: Esmeraldas), Grishin, (Panama: Panama), () Grishin, (Ecuador: Zamora-Chinchipe), () Grishin, (Panama: Darien), () Grishin, (Ecuador: Napo), () Grishin, (Panama: Panama), () Grishin, (Ecuador: Pastaza), Grishin, (Panama: Colón), Grishin, (Ecuador: Napo), Grishin, (Ecuador: Esmeraldas), Grishin, (Guyana), Grishin, (Peru: Cuzco), Grishin, (Peru: Cuzco), Grishin, (Panama: Panama), Grishin, (Brazil: Mato Grosso), () Grishin, (Brazil: Rondônia), () Grishin, (Panama: Panama), () Grishin, (Ecuador: Napo), Grishin, (Brazil: Rondônia), Grishin, (Peru: Loreto), Grishin, (Suriname: Para), Grishin, (Brazil: Santa Catarina), Grishin, (Panama: Panama), Grishin, (Brazil: Santa Catarina), Grishin, (Ecuador: Orellana), Grishin, (Venezuela: Aragua), Grishin, (Guatemala), Grishin, (Guyana), () Grishin, (Panama: Darien), () Grishin, (Mexico: Guerrero.
View Article and Find Full Text PDFHortic Res
January 2025
College of Horticulture and Plant Protection, Henan University of Science and Technology, Luoyang 471023, China.
DNA methylation is a stable epigenetic mark that plays a crucial role in plant life processes. However, the specific functions of DNA methylation in grape berry development remain largely unknown. In this study, we performed whole-genome bisulfite sequencing on 'Kyoho' grape and its early-ripening bud mutant 'Fengzao' at different developmental stages.
View Article and Find Full Text PDFTelomere biology disorders (TBDs) are inherited conditions associated with multisystem manifestations. We describe clinical and functional characterisation of a novel TERT variant. Whole-genome sequencing was performed along with single length analysis ().
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