A single flexible RNAPII-CTD integrates many different transcriptional programs.

Transcription

a Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver , British Columbia , Canada.

Published: March 2016

The RNAPII-CTD functions as a binding platform for coordinating the recruitment of transcription associated factors. Altering CTD function results in gene expression defects, although mounting evidence suggests that these effects likely vary among species and loci. Here we highlight emerging evidence of species- and loci-specific functions for the RNAPII-CTD.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853039PMC
http://dx.doi.org/10.1080/21541264.2016.1163451DOI Listing

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