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Antibacterial carbon dots.
Mater Today Bio
February 2025
Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, PR China.
Bacterial infections significantly threaten human health, leading to severe diseases and complications across multiple systems and organs. Antibiotics remain the primary treatment strategy for these infections. However, the growing resistance of bacteria to conventional antibiotics underscores the urgent need for safe and effective alternative treatments.
View Article and Find Full Text PDFReview on antibacterial flavonoids from genus : Structure-activity relationship and mode of action.
Heliyon
January 2025
Department of Chemical Sciences, Faculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM), 46300, Bangi, Selangor, Malaysia.
The Fabaceae family, particularly genus , is renowned for significant medicinal properties. These plants have been used as natural remedies to address various health issues and are rich in flavonoids. Therefore, this review aimed to provide a comprehensive overview of antibacterial activity, structure-activity relationship, especially against drug-resistance and mode of action for flavonoids isolated from .
View Article and Find Full Text PDFIodoform in Surgical Practice: A Comprehensive Review of Its Historical Evolution, Clinical Applications, and Safety Profiles.
Cureus
December 2024
Department of Neurosurgery, Hurley Medical Center, Flint, USA.
Iodoform, a halogenated organic compound, has been a cornerstone in surgical practice due to its potent antiseptic and antimicrobial properties. This comprehensive review examines the historical evolution, mechanism of action, clinical applications, and safety profile of iodoform across various surgical disciplines. Historically significant formulations like Whitehead's varnish and bismuth iodoform paraffin paste (BIPP) demonstrated remarkable efficacy in wound healing during the late 19th and early 20th centuries.
View Article and Find Full Text PDFEvaluation of the antibacterial properties of four bioactive biomaterials for chronic wound management.
Future Microbiol
January 2025
Department of Biological Sciences, Missouri University of Science and Technology, Rolla, MO, USA.
Aim: Chronic wound infections present a prevalent medical issue and a multifaceted problem that significantly impacts healthcare systems worldwide. Biofilms formed by pathogenic bacteria are fundamental virulence factors implicated in the complexity and persistence of bacterial-associated wound infections, leading to prolonged recovery times and increased risk of infection. This study aims to investigate the antibacterial effectiveness of commonly employed bioactive wound healing compositions with a particular emphasis on their effectiveness against common bacterial pathogens encountered in chronic wounds - , , and to identify optimal wound product composition for managing chronic wound infections.
View Article and Find Full Text PDFComputational Evaluation of Punica granatum Leaf Phytochemicals against Multi-drug Resistant E. coli: Molecular Docking, ADMET, MD Simulation, and DFT Studies.
Curr Comput Aided Drug Des
January 2025
Department of Applied Sciences, Indian Institute of Information Technology, Allahabad, Deoghat, Jhalwa, Prayagraj Uttar Pradesh, 211015, India.
Introduction: Multidrug-resistant (MDR) E. coli presents a significant challenge in clinical settings, necessitating the exploration of novel therapeutic agents. Phytochemicals from Punica granatum (pomegranate) leaves have shown potential antibacterial properties.
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