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Estimation of end-of-outbreak probabilities in the presence of delayed and incomplete case reporting.
Proc Biol Sci
January 2025
Mathematical Institute, University of Oxford, Oxford, UK.
Towards the end of an infectious disease outbreak, when a period has elapsed without new case notifications, a key question for public health policymakers is whether the outbreak can be declared over. This requires the benefits of a declaration (e.g.
View Article and Find Full Text PDFThe WHO Disease Outbreak News during the Covid-19 pandemic.
PLOS Glob Public Health
January 2025
Center for Global Health Science and Security, Georgetown University Medical Center, Washington, DC, United States of America.
During the Covid-19 pandemic, the World Health Organization (WHO) was an important public source of information - not only about the pandemic, but also thousands of other potential health emergencies. Here, we examine the 242 reports published in the WHO Disease Outbreak News (DON) during the first four years of the Covid-19 pandemic (2020 to 2023), and document the diseases and regions that were reported. We find that multinational epidemics of diseases like Ebola virus and MERS-CoV continue to dominate the DON.
View Article and Find Full Text PDFRole of digital technology in epidemic control: a scoping review on COVID-19 and Ebola.
BMJ Open
January 2025
Department of Midwifery, College of Medicine and Health Sciences, Mizan-Tepi University, Mizan Aman, Ethiopia.
Objective: To synthesise the role of digital technologies in epidemic control and prevention, focussing on Ebola and COVID-19.
Design: A scoping review.
Data Sources: A systematic search was done on PubMed, HINARI, Web of Science, Google Scholar and a direct Google search until 10 September 2024.
Identification of Filovirus Entry Inhibitors from Marine Fungus-Derived Indole Alkaloids.
Mar Drugs
January 2025
Nebraska Center for Virology, School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Filoviruses, mainly consisting of the two genera of and , are enveloped negative-strand RNA viruses that can infect humans to cause severe hemorrhagic fevers and outbreaks with high mortality rates. However, we still do not have effective medicines for treating these diseases. To search for effective drugs, we have identified three marine indole alkaloids that exhibit potent activities against filovirus infection.
View Article and Find Full Text PDFQuantitative evaluation of China's public health emergencies response policies: a PMC index model approach.
BMC Public Health
January 2025
Shandong Second Medical University, Weifang, China.
Background: In recent years, public health emergencies, such as the COVID-19 pandemic and Ebola outbreaks, have occurred with increasing frequency worldwide, posing significant threats to global public health security. Policies serve as the foundation and institutional framework for effective emergency responses. Consequently, evaluating and optimizing the formulation and implementation of Public Health Emergency Response Policies (PHERPs) to enhance emergency response capacities has become an urgent and important research priority.
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