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A clinical challenge: delayed diagnosis of autoimmune polyglandular syndrome type II in a patient with thyroid eye disease.
Orbit
January 2025
Department of Ophthalmology and Visual Sciences, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
A 35-year-old woman with thyroid eye disease (TED) was found to have autoimmune polyglandular syndrome type II (APS-II) 1 year after developing symptoms of this rare syndrome, during which she underwent 8 emergency department visits before receiving a targeted endocrinology workup. Thyroid disease is the second most common autoimmune syndrome associated with APS-II after primary adrenal insufficiency. Identification of this syndrome is critical as it can be life-threatening if left untreated.
View Article and Find Full Text PDFAge-related differences in eye blink-related neural activity and functional connectivity during driving.
Heliyon
January 2025
Department of Ergonomics, Leibniz Research Centre for Working Environment and Human Factors, 44139, Dortmund, Germany.
Article Synopsis
- Driving involves complex coordination that deteriorates with age, affecting cognitive and motor functions.
- A study compared blink behavior and neural responses in younger and older adults during reactive and proactive driving tasks, revealing that younger participants had shorter blink durations and more efficient neural processing.
- Functional connectivity analysis indicated that younger adults exhibit stronger network integration in various brain areas, while older adults showed signs of compensatory mechanisms in attention networks, suggesting adaptability in response to cognitive demands.
Comparative analysis of ethical standards for the utilization of Assisted Reproductive Technologies in Brazil: Resolutions from 1992 to 2023.
JBRA Assist Reprod
December 2024
Christus University Center (Unichristus), Fortaleza, CE, Brazil.
Due to its documented records and technological achievements, in vitro embryo creation technology is still honored worldwide forty years after Louise Brown's birth on July 25, 1978. The World Health Organization (WHO) reports that one in six people globally who are of reproductive age may have infertility at some point in their lives. In this environment, it has become noteworthy for couples or patients to want to become pregnant through operations carried out by Assisted Human Reproduction Centers (AHRCs).
View Article and Find Full Text PDFDevelopment of Robust Lane-Keeping Algorithm Using Snow Tire Track Recognition in Snowfall Situations.
Sensors (Basel)
December 2024
Department of Mechanical and Automotive Engineering, Seoul National University of Science and Technology, Seoul 01811, Republic of Korea.
This study proposed a robust lane-keeping algorithm designed for snowy road conditions, utilizing a snow tire track detection model based on machine learning. The proposed algorithm is structured into two primary modules: a snow tire track detector and a lane center estimator. The snow tire track detector utilizes YOLOv5, trained on custom datasets generated from public videos captured on snowy roads.
View Article and Find Full Text PDFIctal SPECT Imaging Findings in Parkinson's Disease with Rapid Eye Movement Sleep Behavior Disorder.
Mov Disord Clin Pract
December 2024
Department of Neurology and Nuclear Medicine, University of Stellenbosch, Cape Town, South Africa.
Background: Rapid eye movement sleep behavior disorder (RBD) is an established prodrome and symptom of synucleinopathies. The pathophysiology of this disorder has been well studied but there is a lack of functional imaging data to illustrate the dysfunction in vivo.
Objectives: We aimed to investigate the functional changes of RBD, by performing ictal REM sleep SPECT, comparing subjects with Parkinson's Disease (PD) and evidence of RBD to subjects with PD and no RBD.
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