Assuring the Proper Analytical Performance of Measurement Procedures for Immunosuppressive Drug Concentrations in Clinical Practice: Recommendations of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Immunosuppressive Drug Scientific Committee.

Ther Drug Monit

*Risch Laboratories Group, Schaan, Principality of Liechtenstein; †Klinikum Stuttgart, Zentralinstitut für Klinische Chemie und Laboratoriumsmedizin, Stuttgart, Germany; ‡iC42 Clinical Research and Development, University of Colorado, Anschutz Medical Campus, Denver; §Pharmacology, APHP, Hôpital Européen G Pompidou, Paris Descartes University, France; ¶Department of Pathology and Genomic Medicine, Houston Methodist Hospital, TX; ‖ASI Ltd, St George's-University of London, United Kingdom; **Pharmacology and Toxicology Laboratory, Biomedical Diagnostic Center (CDB), Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain; ††Clinical Pharmacology Unit, Institute of Cardiology, Medical University of Warsaw, Poland; ‡‡Department of Drug Chemistry, Medical University of Warsaw, Poland; §§Department of Laboratory Medicine and Pathology, Mayo Clinic, College of Medicine, Rochester, NY; ¶¶UMR 850 INSERM, University Limoges, CHU Limoges, France; ‖‖Department of Clinical Pharmacology, Georg-August University, University Medical Center Göttingen, Germany; and ***Clinical Chemistry Department, Université Catholique de Louvain, LTAP, Cliniques Universitaires St Luc, Brussels, Belgium.

Published: April 2016

AI Article Synopsis

  • Monitoring immunosuppressive drugs (ISDs) in blood is crucial for ensuring patient safety and treatment efficacy due to the narrow therapeutic ranges and potential side effects associated with these medications.
  • Accurate and precise measurements are essential for avoiding drug underexposure or overexposure, which can lead to serious health risks.
  • This overview from the Immunosuppressive Drugs Scientific Committee aims to provide a summary and guidance on the best practices for therapeutic drug monitoring (TDM) of ISDs.

Article Abstract

Monitoring immunosuppressive drugs (ISDs) in blood or plasma is still a key therapeutic drug monitoring (TDM) application in clinical settings. Narrow target ranges and severe side effects at drug underexposure or overexposure make accurate and precise measurements a must. This overview prepared by the Immunosuppressive Drugs Scientific Committee of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology is intended to serve as a summary and guidance document describing the current state-of-the-art in the TDM of ISDs.

Download full-text PDF

Source
http://dx.doi.org/10.1097/FTD.0000000000000269DOI Listing

Publication Analysis

Top Keywords

therapeutic drug
12
drug monitoring
12
immunosuppressive drug
8
international association
8
association therapeutic
8
monitoring clinical
8
clinical toxicology
8
scientific committee
8
immunosuppressive drugs
8
drug
6

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!