AI Article Synopsis
- A study on the 70% ethanol extract from the rhizome of Anemone amurensis resulted in the discovery of two new triterpenoid saponins, labeled as compounds 1 and 2.
- Their chemical structures were determined using various analysis techniques including NMR and mass spectrometry.
- Compound 2 demonstrated strong cytotoxic effects on two cancer cell lines, A549 and Hep-G2, with lower IC50 values compared to compound 1, which was less potent.
Article Abstract
Phytochemical investigation of the 70% EtOH extract of the rhizome of Anemone amurensis led to the isolation of two new oleanane-type triterpenoid saponins 1 and 2. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR data, and HR-ESI-MS. Compounds 1 and 2 were tested for cytotoxicities against two human cancer cell lines (A549 and Hep-G2). Compound 2 showed potent cytotoxicity with IC50 values of 38.53 and 66.17 μM, respectively, while compound 1 with IC50 > 100 μM.
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| http://dx.doi.org/10.1080/10286020.2016.1142974 | DOI Listing |
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