[MRI-characteristics of epileptogenic supratentorial brain tumors in children].

Zh Nevrol Psikhiatr Im S S Korsakova

FGBU 'Rossijskaja detskaja klinicheskaja bol'nitsa' Minzdrava RF, Moskva.

Published: April 2016

Objective: To analyze MR-images in patients with symptomatic epilepsy associated with the brain tumor.

Material And Methods: MRI results of 52 patients with symptomatic epilepsy operated for tumors of supratentorial localization were analyzed. The most epileptogenic tumors with atypical MRI signs and subtle clinical presentation were identified. All patients with tumors were operated using different methods of surgical intervention.

Results: Dysembryoplastic neuroepithelial tumors (DNET), diffuse astrocytomas (DA) and gangliogliomas (GG) were the most frequent epileptogenic tumors. In all the cases of DNET and in 4 patients with GG, epileptic seizures were the first, and in 4 of 5 cases of DIO were the only clinical sign of tumor presence. In DNET, DA and GG, there was an iso- or hypointensive signal on T1 WI and a signal varying in intensity from moderate to hyperintense in T2 and FLAIR WI, while in cases with DNET and GG, no mass effect and perifocal edema was practically seen. The so-called «spume-like» (multicystic) structure was most clearly observed in FLAIR WI. No significant changes in the dimensions of the DNET and GG were identified. The combination of DNET with focal cortical dysplasia was noted in one case. In DA, it was difficult to distinguish the perifocal edema from tumorous tissue and normal brain tissues, and the growth potential of malformation was slow.

Conclusion: Epileptogenic tumors can imitate the x-ray characteristics of each other, and mimicry to gangliogliomas, oligodendrogliomas and astrocytomas Gr I, II, and others. They are the most frequent causes of symptomatic focal epilepsy. The presence of these malformations is necessary to exclude first of all in all cases of pharmacoresistant epilepsy.

Download full-text PDF

Source
http://dx.doi.org/10.17116/jnevro20161161156-63DOI Listing

Publication Analysis

Top Keywords

epileptogenic tumors
12
patients symptomatic
8
symptomatic epilepsy
8
cases dnet
8
perifocal edema
8
tumors
7
dnet
6
[mri-characteristics epileptogenic
4
epileptogenic supratentorial
4
supratentorial brain
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!