The Pluripotency of Neural Crest Cells and Their Role in Brain Development.

Curr Top Dev Biol

INSERM U968, Paris, France; Sorbonne Universités, UPMC Univ Paris 06, UMR S 968, Institut de la Vision, Paris, France; CNRS, UMR 7210, Paris, France.

Published: December 2016

The neural crest (NC) is, in the Chordate phylum, an innovation of vertebrates, which exhibits several original characteristics: its component cells are pluripotent and give rise to both ectodermal and mesodermal cell types. Moreover, during the early stages of neurogenesis, the NC cells exert a paracrine stimulating effect on the development of the preotic brain.

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http://dx.doi.org/10.1016/bs.ctdb.2015.10.008DOI Listing

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