Analysed were 3700 case records of the patients suffering from diabetes mellitus in order to establish direct indications for transplantation of small pancreatic segments. In procurement of the pancreas from 86 cadavers, it was established, that the subjects at the age under 40 were the ideal donors. In 34 experiments, the possibility of the performance of adequate conservation of the pancreas up to 6-8 h by the perfusion-free hypothermic method, intraorganic normothermal perfusion, transplant placing into the continuously oxygenated perfluoran solution or diluted blood, or in combined use of the two latter methods is shown. The results of 40 experiments on the dogs indicate that preservation and transplantation of 1/4-1/8 of the pancreatic mass are sufficient for maintaining normoglycemia.
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