Objective: To study the clinical profile and outcome in children with diphtheritic polyneuropathy (DP).
Methodology: 13 children with polyneuropathy were included in this study. Their demographic profile, age, sex and immunization status were recorded. Detailed clinical and neurological examination was done. Investigations like CSF analysis, NCV studies, MRI brain were done. The results were tabulated and analyzed.
Results: All the children presented with bulbar palsy and had h/o membranous tonsillitis. Isolated palatal palsy was seen in 7 children (53%). 6 (46.1%) children developed quadriparesis. 1 child expired and recovery is complete in rest of the 12 children. Children with isolated bulbar palsy recovered within 2 to 4 weeks while children with quadriparesis recovered within 5-6 wks.
Conclusions: Any child diagnosed with diphtheria should be followed for 3-6 months in anticipation of neurological complications. DP carries good prognosis hence timely diagnosis and differentiation from other neuropathies is a prerequisite for rational management.
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http://dx.doi.org/10.4103/1817-1745.174441 | DOI Listing |
Pediatr Infect Dis J
August 2024
Department of Paediatrics, Mayotte Hospital, Mamoudzou, France.
J Assoc Physicians India
March 2023
Junior Resident, Department of Medicine, Mysore Medical College and Research Institute, Mysuru, Karnataka, India; Corresponding Author.
Diphtheria is showing a resurgence in recent years. A fall in the immunity of adults to diphtheria due to multiple reasons is showing a rise in diphtheria cases in the adult population. Diphtheritic polyneuropathy shows a prevalence of 20-27% of infections.
View Article and Find Full Text PDFJ Pediatr Neurosci
September 2019
Department of Tropical Medicine, Hainan Medical University, Haiko, China.
J Pediatr Neurosci
January 2018
Department of Paediatrics, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.
Aim: To study the spectrum of neurological complications of diphtheria, timing of onset with respect to respiratory disease, and pattern of recovery.
Settings And Design: Prospective, observational, hospital-based study conducted in tertiary care hospital.
Materials And Methods: Twenty-eight cases of diphtheria with neurological complications were admitted during the period of study.
Clin Auton Res
February 2018
Neurology Department, Raigmore Hospital, Inverness, UK.
Objectives: To review infectious diseases that may cause autonomic dysfunction.
Methods: Review of published papers indexed in medline/embase.
Results: Autonomic dysfunction has been reported in retrovirus (human immunodeficiency virus (HIV), human T-lymphotropic virus), herpes viruses, flavivirus, enterovirus 71 and lyssavirus infections.
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