AI Article Synopsis
- Modifying blood flow can improve blood perfusion by changing the properties of blood, such as through hemodilution, defibrinogenation, or using oral drugs.
- Hemodilution is known to be clinically effective for specific conditions, while the effectiveness of enzymatic defibrinogenation is still uncertain.
- There are several drugs that have been shown to work well in altering blood flow, but it's unclear if their effects are solely due to changes in blood flow dynamics.
Article Abstract
One of the possibilities to ameliorate blood perfusion is the modification of the rheological properties of blood. Hemodilution, enzymatic defibrinogenation and oral drugs are available at present to achieve this aim. Hemodilution is clinically successful with certain indications. The efficacy of enzymatic defibrinogenation cannot be judged finally. Within the group of rheologically active drugs a variety of substances are of proven effectiveness. Yet it is open whether this is brought about exclusively by hemorheological mechanisms.
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