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| http://dx.doi.org/10.11604/pamj.2015.22.263.8080 | DOI Listing |
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Department of Chemistry, Binghamton University, the State University of New York, Binghamton, New York 13902, United States.
RNA interference (RNAi) has rapidly matured as a novel therapeutic approach. In this field, chemical modifications have been critical to the clinical success of short interfering RNAs (siRNAs). Notwithstanding the significant advances, achieving robust durability and gene silencing in extrahepatic tissues, as well as reducing off-target effects of siRNA, are areas where chemical modifications can still improve siRNA performance.
View Article and Find Full Text PDFLow-Intensity Online Intervention for Mental Distress Among Help-Seeking Young People in Hong Kong: A Randomized Clinical Trial.
JAMA Netw Open
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Department of Psychiatry, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong.
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Comparative analysis of kidney function prediction: traditional statistical methods vs. deep learning techniques.
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Kawasaki Medical School, Department of Nephrology and Hypertension, Kurashiki, Japan.
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View Article and Find Full Text PDFHIV Prevention in Syringe Service Programs Since the Start of COVID-19: Where Do We Go From Here?
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Columbia University Irving Medical School, New York, NY, USA.
Purpose: This narrative review addresses post-2020, specific, complex challenges for use of and adherence to pre-exposure prophylaxis (PrEP) for HIV prevention among out-of-treatment people who use drugs (PWUD) at syringe services programs (SSPs).
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Objective surgical skill assessment based on automatic recognition of dissection and exposure times in robot-assisted radical prostatectomy.
Langenbecks Arch Surg
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Department for the Promotion of Medical Device Innovation, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
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