Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765971 | PMC |
| http://dx.doi.org/10.1177/003335491613100206 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Third-Hand Smoke Exacerbates HO-Driven Airway Responses in A549 Cells.
Turk J Pharm Sci
November 2024
Yeditepe University Faculty of Pharmacy, Department of Toxicology, İstanbul, Türkiye.
Article Synopsis
- Third-hand smoke (THS) is harmful residual smoke that remains on surfaces and can negatively affect respiratory health, especially in individuals with preexisting conditions.
- The study investigated how THS causes respiratory toxicity through mechanisms like increased reactive oxygen species (ROS), cytotoxicity, and inflammation in human airway cells.
- Findings indicated that THS leads to oxidative stress, as evidenced by increased levels of malondialdehyde and interleukin-6, along with decreased antioxidant activity, potentially exacerbating respiratory diseases.
Elucidating tobacco smoke-induced craniofacial deformities: Biomarker and MAPK signaling dysregulation unraveled by cross-species multi-omics analysis.
Ecotoxicol Environ Saf
December 2024
Department of Burns and Plastic Surgery, The Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, PR China. Electronic address:
Article Synopsis
- Tobacco smoke, especially secondhand and thirdhand, is a significant environmental threat linked to craniofacial malformations, with research utilizing zebrafish larvae showing that higher concentrations of cigarette smoke extract correlate with increased severity of these malformations.
- Through a detailed analysis, specific microRNAs (miR-96-5p, miR-152, miR-125b-2-3p, and miR-181a-3-3p) were identified as key indicators in cartilage development, revealing their relationship with the MAPK signaling pathway and oxidative stress.
- This study’s cross-species approach validated findings in human embryonic cells, uncovering critical genes and protein interactions that could lead to better diagnostic and treatment strategies for
Potential health risk of human exposure to tobacco-specific nitrosamines in second-hand and third-hand smoke.
J Hazard Mater
December 2024
Key Laboratory of Pollution Control and Ecosystem Restoration in Industry Clusters (Ministry of Education), School of Environment and Energy, South China University of Technology, Guangzhou 510006, China. Electronic address:
Article Synopsis
- Environmental tobacco smoke (ETS), which includes second-hand (SHS) and third-hand smoke (THS), poses significant health risks, particularly for non-smokers and children who have higher exposure levels.
- The study analyzed tobacco-specific nitrosamines (TSNAs) from SHS and THS in a controlled room, finding differences in their concentration and distribution due to various factors like air exchange and particle deposition.
- The research highlighted that even limited exposure to THS leads to a concerning lifetime cancer risk, indicating the need for stronger smoke-free policies to mitigate health risks from ETS.
Long-term exposure to third-hand smoke could accelerate biological aging via mitochondrial dysfunction: Evidence from population and animal studies.
J Hazard Mater
December 2024
Department of Nutrition and Food Hygiene, School of Public Health, Key Laboratory of Precision Nutrition and Health, Ministry of Education, Harbin Medical University, 157 Baojian Road, Harbin, Heilongjiang 150081, China. Electronic address:
The relationship between third-hand smoke (THS) exposure and lifespan remains inadequately explored. Our study sought to clarify the effects of THS on aging and lifespan. In this pursuit, our cross-sectional analysis assessed hematological aging markers in 986 non-smokers and examined lifespan alterations using a Drosophila model.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!