Eosinophilic colitis.

BMJ Case Rep

Department of Medical Oncology, Portuguese Institute of Oncology Francisco Gentil, Coimbra, Portugal.

Published: March 2016

A 57-year-old man, diagnosed with colon cancer stage III in July/2010, underwent surgery and received adjuvant chemotherapy with FOLFOX 4 (5-fluorouracil; calcium folinate and oxaliplatin), which ended in March/2011 after 12-cycles. It was then decided to maintain periodical surveillance. About 1 year later, the patient developed several episodes of diarrhoea, mainly during the night, and presented persistent peripheral eosinophilia in the blood count (range 585-1300 eosinophils/µL). Colonoscopy was performed, with the histological result showing eosinophilic infiltration of the colon, compatible with eosinophilic colitis. The patient was treated with a short course of budesonide, achieving resolution of symptoms, and has remained asymptomatic.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785455PMC
http://dx.doi.org/10.1136/bcr-2016-214496DOI Listing

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