After a description of the harmful effects of psychotropic drugs as well as of the moments of vulnerability to any teratogenic effect, this paper reviews prospective, retrospective and epidemiological studies of the teratogenic effects of anticonvulsants (phenytoin, valproic acid, carbamazepine and barbiturates), lithium, anti-psychotics, benzodiazepines and anti-depressive agents. It is found that the results of these studies are not unequivocal. Only lithium and valproic acid are shown to be teratogenic. In cases where malformations of the fetus are observed, the treatment often consisted in a combination of various psychotropic drugs. The review is completed with data on the psychopharmacological problems during delivery and their side-effects on the newborn.

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0924270800034128DOI Listing

Publication Analysis

Top Keywords

psychotropic drugs
12
valproic acid
8
congenital malformations
4
malformations caused
4
caused psychotropic
4
drugs pregnancy
4
pregnancy description
4
description harmful
4
harmful effects
4
effects psychotropic
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!