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PET detectors with depth-of-interaction and time-of-flight capabilities.
Radiol Phys Technol
September 2024
National Institutes for Quantum Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, 263-8555, Japan.
In positron emission tomography (PET), measurements of depth-of-interaction (DOI) information and time-of-flight (TOF) information are important. DOI information reduces the parallax error, and TOF information reduces noise by measuring the arrival time difference of the annihilation photons. Historically, these have been studied independently, and there has been less implementation of both DOI and TOF capabilities because previous DOI detectors did not have good TOF resolution.
View Article and Find Full Text PDFCracking the code: interpreting content and phrases used in maternal-fetal medicine fellowship letters of recommendation.
Am J Obstet Gynecol MFM
August 2024
Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN (Shanks).
Background: Letters of recommendation for Maternal-Fetal Medicine(MFM) fellowship are a critical part of the applicant selection process. However, data regarding best practices for how to write LOR for MFM is limited. Similarly, within letters of recommendation, differences in the "code" or meaning of summative words/phrases used at the end of letters of recommendation are seen between surgery, pediatrics, and medicine.
View Article and Find Full Text PDFA conformal TOF-DOI Prism-PET prototype scanner for high-resolution quantitative neuroimaging.
Med Phys
January 2023
Department of Radiology, Weill Cornell Medical College, Cornell University, New York, New York, USA.
Background: Positron emission tomography (PET) has had a transformative impact on oncological and neurological applications. However, still much of PET's potential remains untapped with limitations primarily driven by low spatial resolution, which severely hampers accurate quantitative PET imaging via the partial volume effect (PVE).
Purpose: We present experimental results of a practical and cost-effective ultra-high resolution brain-dedicated PET scanner, using our depth-encoding Prism-PET detectors arranged along a compact and conformal gantry, showing substantial reduction in PVE and accurate radiotracer uptake quantification in small regions.
High-resolution and high-sensitivity PET for quantitative molecular imaging of the monoaminergic nuclei: A GATE simulation study.
Med Phys
July 2022
Department of Radiology, Renaissance School of Medicine, Stony Brook University, Stony Brook, New York, USA.
Article Synopsis
- A new high-resolution and high-sensitivity brain-dedicated PET scanner has been developed to improve molecular imaging of small brain structures, addressing the limitations of traditional PET imaging regarding spatial resolution.
- The scanner utilizes a novel design with depth-encoding Prism-PET detector modules in a unique geometric arrangement to reduce partial volume effects and enhance the accuracy of radiotracer uptake measurements in small brain areas.
- Validation methods included Monte Carlo simulations and phantom studies, demonstrating that the scanner with 1.5 mm crystals outperforms the one with 1 mm crystals by providing improved depth-of-interaction resolution essential for accurate imaging.
Evaluating and Engaging: Using Participatory Video With Kenyan Secondary School Students to Explore Engagement With Health Research.
Front Public Health
April 2022
The KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.
Background: The growing ethical requirement to engage communities with health research has yielded diversification in approaches and targeted audiences. Conventional approaches like community "town-hall meetings," laboratory open-days and focus group discussions, have evolved into new methods and audiences such as community drama and school engagement with health research (SEHR) involving learning interactions between researchers and school students. While engagement practices are diversifying, evaluations of these initiatives are rare in Low- and Middle-Income Countries (LMIC).
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