AI Article Synopsis
- Tetrabenazine is a medication used to treat conditions like chorea, tardive dyskinesia, tics, and dystonia, but it can rarely lead to complications such as acute eyeball dystonia.
- A case study is presented where a patient with severe tics developed an acute oculogyric crisis after 8 days of tetrabenazine treatment, despite having no previous dystonic reactions.
- The symptoms resolved within a week after stopping the medication, highlighting the potential for tetrabenazine to induce such crises and the challenges in distinguishing between drug-induced dystonia and dystonic tics in Tourette syndrome patients.
Article Abstract
Tetrabenazine is used in the treatment of chorea, tardive dyskinesia, tics, and dystonia. It rarely causes acute eyeball dystonia and the description of this complication in Gilles de la Tourette syndrome is limited. We provide a description of an acute oculogyric crisis caused by tetrabenazine in a patient with severe tics. The patient had never developed acute dystonic reactions, although he was previously exposed to numerous dopamine receptor-blocking agents. After 8 days of therapy with tetrabenazine at a dose of 62.5 mg daily, the patient developed involuntary movement of the eyeballs. Withdrawal of tetrabenazine caused resolution of all symptoms after a week. The purpose of this description is to draw attention to the potential of tetrabenazine to induce acute oculogyric crisis as well as the difficulty of differentiating drug-induced dystonia from dystonic tics in patients with Gilles de la Tourette syndrome.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772939 | PMC |
| http://dx.doi.org/10.2147/NDT.S98694 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!