AI Article Synopsis
- The study investigates the effects of remote ischaemic preconditioning (RIPC) on ECG changes during exercise in healthy individuals, as its benefits are well-documented in surgical settings but not clearly understood in sports performance.
- A group of 17 participants underwent two exercise tests while being randomly assigned to either a control group or a RIPC intervention, which involved cycles of ischaemia and reperfusion before the exercises.
- Results showed significant shortening of QT intervals during exercise for those who underwent RIPC compared to the control group, without any divergent effects on RR intervals, indicating that RIPC impacts heart rate-independent measures during physical activity.
Article Abstract
Unlabelled: The protective action of remote ischaemic preconditioning (RIPC) has been demonstrated in the context of surgical interventions in cardiology. Application of RIPC to sports performance has been proposed, but its effect on the electrocardiogram (ECG) during exercise remains unknown. This exploratory study aims to measure the changes in ventricular repolarization observed during exercise following RIPC in healthy subjects. In an experimental randomized crossover study, 17 subjects underwent two bouts of constant load exercise tests at 75% and 115% of gas exchange threshold (GET). Prior to exercise, they were allocated to either control or RIPC intervention with four cycles of 5 min of ischaemia followed by 5 min of reperfusion. ECG was continuously recorded during the protocol. QT and RR intervals were measured every 30 s (on an average tracing of the preceding 10 s). Although the time course of RR intervals did not differ between the two interventions (p = .56 at 75% GET and p = .74 at 115% GET), a significant shortening of QT intervals (measured from Q onset to T end) was observed during exercise (mean ± standard deviation of RIPC vs.
Control: -32 ± 19 ms at 75% GET (p < .001) and -34 ± 12 ms at 115% GET (p < .001)) as well as during recovery (-21 ± 8 ms at 75% GET (p < .001) and -16 ± 11 ms at 115% GET (p < .001)). This effect was not present at rest. These RIPC-related changes were clearly identifiable on the QT-RR loops after hysteresis reduction. RIPC therefore induces heart rate-independent shortening of QT intervals that is revealed during exercise.
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| http://dx.doi.org/10.1080/17461391.2016.1156161 | DOI Listing |
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