AI Article Synopsis

  • Conducted a 28-year study on enteric fever at a pediatric center, revealing trends in the disease's occurrence.
  • Most cases were in children who traveled to the Indian subcontinent, indicating a link to international travel.
  • Found high levels of antibiotic resistance, low vaccination rates, and notable delays in diagnosis and treatment for affected children.

Article Abstract

We undertook a 28-year review of enteric fever at a large tertiary care pediatric center. Most cases occurred in children who visited friends and relatives in the Indian subcontinent, and there was significant antibiotic resistance. Documented vaccination rates were low, and many cases also had evidence of delays in diagnosis and treatment.

Download full-text PDF

Source
http://dx.doi.org/10.1093/jpids/piw007DOI Listing

Publication Analysis

Top Keywords

enteric fever
8
tertiary care
8
care pediatric
8
28-year review
8
fever multicultural
4
multicultural canadian
4
canadian tertiary
4
pediatric setting
4
setting 28-year
4
review undertook
4

Similar Publications

This was an original study that mainly explored the effect of probiotic therapy and personalized nursing on immune function in children with acute gastroenteritis. One hundred and twelve (112) children with acute gastroenteritis were selected and divided into an intervention group and a control group. The control group accepted omeprazole enteric-coated capsules and routine nursing.

View Article and Find Full Text PDF

Context: Anemia is a medical condition resulting from a reduction in the number of red blood cells below the reference range. It is a major public health problem, particularly among adolescents, as it can have negative effects on cognitive performance, growth and reproduction. This study aims to assess the determinants of anemia among adolescents in schools in the city of Douala.

View Article and Find Full Text PDF

Background: Enteric fever caused by Salmonella enterica serovars Typhi and Paratyphi A in addition to gastroenteritis and invasive disease, predominantly attributable to nontyphoidal Salmonella serovars Typhimurium and Enteritidis, are major causes of death and disability across the globe. A broad-spectrum vaccine that protects against disease caused by typhoidal and nontyphoidal serovars of Salmonella is not available for humans but would prevent a considerable burden of disease worldwide.

Methods: We previously developed a broad-spectrum vaccine for Gram-negative bacteria that is based on the inner core domain of detoxified Escherichia coli O111, Rc (J5) mutant lipooligosaccharide, a highly conserved antigen across Gram-negative bacteria, complexed with an outer membrane protein of group B Neisseria meningitidis.

View Article and Find Full Text PDF

Vi capsular polysaccharide of Salmonella enterica serovar Typhi disturbs autophagy to increase intracellular survival in macrophages.

Microb Pathog

December 2024

Department of Laboratory Medicine, Affiliated Hospital, Jiangsu University, Zhenjiang, Jiangsu 212001, China. Electronic address:

The autophagy pathway plays a crucial role in resistance to bacterial infection in the host. Salmonella enterica serovar Typhi (S. Typhi), a human restricted pathogen, causes a systemic infection known as typhoid fever.

View Article and Find Full Text PDF

Introduction: Typhoid fever is an infectious disease primarily caused by sv. Typhi ( Typhi), a bacterium that causes as many as 20 million infections and 600,000 deaths annually. Asymptomatic chronic carriers of S.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!