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- Researchers studied strokes from 1990 to 2021 to understand how many people get them and how they are affected around the world.
- In 2021, strokes caused about 7.3 million deaths and were a major cause of health problems, especially in specific regions like Southeast Asia and Oceania.
- There are differences in stroke risks based on where people live and their age, and some areas actually saw more strokes happening since 2015.
Identifying Differential Methylation in Cancer Epigenetics via a Bayesian Functional Regression Model.
Biomolecules
May 2024
Lady Davis Institute for Medical Research, Montreal, QC H3T 1E2, Canada.
DNA methylation plays an essential role in regulating gene activity, modulating disease risk, and determining treatment response. We can obtain insight into methylation patterns at a single-nucleotide level via next-generation sequencing technologies. However, complex features inherent in the data obtained via these technologies pose challenges beyond the typical big data problems.
View Article and Find Full Text PDFAnisotropic remixing of a phase separated binary colloidal system with particles of different sizes in an external modulation.
J Chem Phys
June 2024
Department of Physics, Lady Brabourne College, P-1/2, Suhrawardy Ave., Kolkata 700017, India.
We explore the phase behavior of a binary colloidal system under external spatially periodic modulation. We perform Monte Carlo simulations on a binary mixture of big and small repulsive Lennard-Jones particles with a diameter ratio of 2:1. We characterize structure by isotropic and anisotropic pair correlation functions, cluster size distribution, bond angle distribution, order parameter, and specific heat.
View Article and Find Full Text PDFPresentation and management of delayed bronchopleural fistula after pulmonary lobectomy: a case report.
J Cardiothorac Surg
May 2024
Department of General Surgery, King Hussein Cancer Center, Amman, Jordan.
Background: Lung cancer is the second most diagnosed cancer and the leading cause of cancer deaths worldwide. Surgical lung resection is the best treatment modality in the early stages of lung cancer as well as in some locally advanced cases. Postoperative air leak is one of the most common complications after pulmonary resection with incidence ranging between 20 and 33%.
View Article and Find Full Text PDFExamining the interaction between prenatal stress and polygenic risk for attention-deficit/hyperactivity disorder on brain growth in childhood: Findings from the DREAM BIG consortium.
Dev Psychobiol
May 2024
Department of Child and Adolescent Psychiatry and Psychology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
This study explored the interactions among prenatal stress, child sex, and polygenic risk scores (PGS) for attention-deficit/hyperactivity disorder (ADHD) on structural developmental changes of brain regions implicated in ADHD. We used data from two population-based birth cohorts: Growing Up in Singapore Towards healthy Outcomes (GUSTO) from Singapore (n = 113) and Generation R from Rotterdam, the Netherlands (n = 433). Prenatal stress was assessed using questionnaires.
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