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Evaluation of Score for Neonatal Acute Physiology and Perinatal Extension II and Clinical Risk Index for Babies with additional parameters. | LitMetric

AI Article Synopsis

  • The study aimed to assess mortality risk in newborns by calculating SNAP-PE-II and CRIB scores, while also evaluating how antenatal corticosteroid and surfactant treatments affect mortality outcomes.
  • Conducted across five centers in Southern Turkey from July 2012 to July 2013, the research involved 1,668 newborns admitted to a neonatal intensive care unit within 12 hours of birth, with various scoring systems applied to determine mortality rates.
  • Results showed that SNAP-PE-II was a more significant predictor of mortality than CRIB, particularly for newborns weighing less than 1,500 g, and using antenatal corticosteroids alongside SNAP-PE-II enhanced mortality prediction accuracy.

Article Abstract

Background: The aim of this study was to determine mortality risk by calculating Score for Neonatal Acute Physiology and Perinatal Extension II (SNAP-PE-II) and Clinical Risk Index for Babies (CRIB) score, and evaluate prediction of the effects of antenatal corticosteroid and surfactant treatment on mortality.

Methods: This multicenter study was conducted simultaneously in five different centers in four different provinces in Southern Turkey between July 2012 and July 2013. A total of 1668 inborn subjects hospitalized in the neonatal intensive care unit within the first 12 h of delivery, and meeting the selection criteria, were included in the study, and CRIB and SNAP-PE-II were used to determine mortality.

Results: The SNAP-PE-II scoring system was applied to all patients, and the CRIB scoring system was used for 310 newborns with gestational age <32 weeks and weighing <1500 g. Of the 1668 patients, 188 died (mortality rate, 11.3%). Cut-off was found to vary with center, which changed specificity and sensitivity of the mortality scores. SNAP-PE-II significantly predicted mortality (P < 0.05) compared with CRIB. SNAP-PE-II also successfully predicted mortality in the group receiving antenatal corticosteroid compared with the group not receiving antenatal corticosteroid.

Conclusion: SNAP-PE-II was a significant predictor of mortality in newborns with birthweight <1500 g compared with CRIB, and assessment of antenatal corticosteroid use in conjunction with SNAP-PE-II increased the accuracy of the prediction of mortality.

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Source
http://dx.doi.org/10.1111/ped.12973DOI Listing

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