Cancer vaccines that have utilized various immunization strategies to induce antitumor immunity have largely failed in clinical settings. We have recently developed a cancer vaccine using a cytomegalovirus (CMV) based vector that expressed a modified melanoma antigen that elicited a robust antitumor CD8 T cell response and tumor rejection.

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http://dx.doi.org/10.1080/2162402X.2015.1056974DOI Listing

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