Codependent development and Th17-to-FoxP3 T cell inter-conversion account for the enigmatic coexistence of IL17-producing and FoxP3 cells in tumor-associated inflammation. In addition to T cells, exTh17-FoxP3 cells present a novel subpopulation of FoxP3 cells. Yin-yang of IL17 and FoxP3 cells presents an important principle for improved approaches in cancer immunotherapy.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760333 | PMC |
| http://dx.doi.org/10.1080/2162402X.2015.1040217 | DOI Listing |
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