AI Article Synopsis
- This study investigates how high-normal blood pressure (HNBP) during the early second trimester can predict hypertensive disorders in pregnancy.
- It analyzed data from 2,143 pregnant women and found that those with HNBP were more likely to develop gestational hypertension (GH) and preeclampsia (PE) compared to those with normal blood pressure.
- The results suggest that HNBP is a significant risk factor for developing GH and PE during pregnancy, indicating early monitoring and intervention may be essential.
Article Abstract
Objective: The aim of this study was to determine the predictive value of high-normal blood pressure (HNBP) during the early second trimester for hypertensive disorders in pregnancy, including gestational hypertension (GH) and preeclampsia (PE).
Methods: This was a retrospective single-center cohort study of 2143 singleton pregnant women. The association of HNBP, ranging from 130/85 to 139/89 mmHg between 14 and 19 weeks of gestation, with the development of hypertensive disorders was assessed by multivariable logistic regression analyses.
Results: In a cohort of 2102 pregnant women, 93 (4.4%) pregnancies had HNBP during early second trimester. Pregnant women with HNBP more frequently developed hypertensive disorders than normotensive women (20.4% vs. 8.2%, p < 0.001). HNBP was significantly associated with the development of GH (adjusted odds ratio (aOR): 1.81; 95% confidence interval (CI): 1.16-3.25, p = 0.015) and PE (aOR: 6.05; 95% CI: 3.46-12.6, p = 0.013) after adjustment for confounders.
Conclusion: HNBP during the early second trimester is an independent risk factor for both GH and PE.
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| http://dx.doi.org/10.3109/10641955.2016.1139719 | DOI Listing |
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