AI Article Synopsis
- Tissue perfusion issues significantly contribute to organ dysfunction, which can lead to worse outcomes after cardiac surgery.
- A study analyzed 220 patients post-cardiac surgery, measuring central venous-arterial difference in CO tension (ΔCO) at various time points to evaluate its relation to outcomes.
- The findings revealed that a low ΔCO (below 6 mmHg) was linked to higher SOFA scores and mortality rates; however, ΔCO had a low predictive value for outcomes in cardiac surgery, contrary to other surgical contexts.
Article Abstract
Alteration of tissue perfusion is a main contributor of organ dysfunction. In cardiac surgery, the importance of organ dysfunction is associated with worse outcome. Central venous-arterial difference in CO tension (ΔCO) has been proposed as a global marker of the adequacy of tissue perfusion in shock states. We hypothesized that ΔCO could be increased in case of postoperative organ failure or worse outcome. In this monocentric retrospective cohort study, we retrieved, from our database, 220 consecutive patients admitted in intensive care after an elective cardiac surgery. Four time points were formed: ICU admission, and 6, 24 and 48 h after. A ΔCO below 6 mmHg defined the normal range values. The SOFA score, intensive care unit and hospital length of stay, hospital and 6-month mortality rate were recorded. We compared patient with low ΔCO (<6 mmHg) and high ΔCO (≥6 mmHg). We included 55 (25 %) and 165 patients in low and high ΔCO groups, respectively. The SOFA score, the hospital and 6 months mortality rate were higher in patients with low ΔCO. Surprisingly, we did not find results previously published in other surgical settings. In cardiac surgery, ΔCO has a low predictive value of outcome.
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| http://dx.doi.org/10.1007/s10877-016-9855-3 | DOI Listing |
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