Chronic nonbacterial osteomyelitis is an autoinflammatory disease occurring mainly in children and adolescents, typically involving recurrent or persistent osteitic foci. The symptom is bone pain, possibly accompanied by soft tissue tenderness. Some patients exhibit symptoms of systemic inflammation. The. precise etiology of the disease is not known, but an imbalance of inflammatory and anti-inflammatory cytokines is presumed to play a role in the development of the disease. While an anti-inflammatory analgesic is in most cases sufficient to calm down the osteitis, the use of corticosteroids, anti- TNF-a inhibitors or bisphosphonates is required in some cases.
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Article Synopsis
- - The case report discusses treating a child with chronic non-bacterial osteomyelitis (CNO) in the jaw, which is a rare, non-infectious condition.
- - The patient showed symptoms like facial swelling and pain, and various medical tests helped confirm the diagnosis, though the cause was unclear.
- - Successful management of CNO involves a team-based approach among different specialties, and orthodontic treatment should be customized based on individual patient needs.
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