By understanding common motivations for participating in observational research studies, clinicians may better understand the perceived benefits of research participation from their clients' perspective. We enrolled 164 cardiac patients in a study about the effects of gratitude and optimism. Two weeks post-enrollment, participants completed a four-item questionnaire regarding motivations for study enrollment. Altruistic motivation ranked highest, while intellectual, health-related, and financial motivations rated lower. Four subgroups of participants emerged, each with distinct characteristics and different priorities for participating. These findings may help front-line clinicians to understand which motivations for participation apply to their clients who enroll in non-treatment-based research projects.
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http://dx.doi.org/10.1080/00981389.2015.1114064 | DOI Listing |
BMC Psychol
December 2024
Department of Behavioral Sciences, Zefat Academic College, Safed, Israel.
Road safety is a critical concern worldwide, impacting individuals, communities, and societies. As mobility increases, so does the risk of accidents and injuries on roads, emphasizing the need for preventive measures. Road safety volunteers contribute significantly to promoting and maintaining road safety, making it important to understand their motivations and resilience sources.
View Article and Find Full Text PDFBMC Med Educ
December 2024
Nursing Department, Shuguang Hospital Affiliated to Shanghai University of TCM, Shanghai, China.
Background: Integration of clinical medicine and other subjects has laid more emphasis on the cultivation of high-quality medical talents, with the increasing demand for interprofessional education (IPE). IPE has been promoted by a number of universities to create and sustain authentic IPE activities, with which students can engage. Although IPE has achieved certain results, there are still many problems.
View Article and Find Full Text PDFObjective: To understand the perinatal experiences of women with gestational diabetes mellitus (GDM) who intended to breastfeed.
Design: Qualitative descriptive study.
Setting/local Problem: Women with GDM and their infants benefit from breastfeeding but have lower exclusive breastfeeding rates than women without GDM, and the reasons for these differences are not entirely clear.
Bioinform Adv
December 2024
Laboratory of Experimental Biophysics, Center for Advanced Technologies, Tashkent, 100174, Uzbekistan.
Motivation: Understanding the conformational landscape of protein-ligand interactions is critical for elucidating the binding mechanisms that govern these interactions. Traditional methods like molecular dynamics (MD) simulations are computationally intensive, leading to a demand for more efficient approaches. This study explores how multiple sequence alignment (MSA) clustering enhance AF-Multimer's ability to predict conformational landscapes, particularly for proteins with multiple conformational states.
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December 2024
Department of Protein Evolution, Max Planck Institute for Biology, Tübingen 72076, Germany.
Motivation: Coiled coils are a widespread structural motif consisting of multiple α-helices that wind around a central axis to bury their hydrophobic core. While AlphaFold has emerged as an effective coiled-coil modeling tool, capable of accurately predicting changes in periodicity and core geometry along coiled-coil stalks, it is not without limitations, such as the generation of spuriously bent models and the inability to effectively model globally non-canonical-coiled coils. To overcome these limitations, we investigated whether dividing full-length sequences into fragments would result in better models.
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