Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3122
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Adrenocortical carcinoma is a rare cancer with poor prognosis. We report a case of metastatic adrenocortical carcinoma in a 61-year-old man successfully treated with multimodal therapy. A left adrenal tumor was detected incidentally in the patient and an adrenalectomy was performed. The pathological diagnosis was adrenocortical carcinoma, stage II. After 1 year, multiple local recurrences were detected in the retroperitoneum space. The patient underwent a metastasectomy and received three courses of adjuvant chemotherapy consisting of etoposide, doxorubicin, and cisplatin plus mitotane. No obvious recurrence has been observed in the 60 months since the treatment.
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