IsoDAR (Isotope Decay-At-Rest) is a novel experiment designed to measure neutrino oscillations through ν̄(e) disappearance, thus providing a definitive search for sterile neutrinos. In order to generate the necessary anti-neutrino flux, a high intensity primary proton beam is needed. In IsoDAR, H2(+) is accelerated and is stripped into protons just before the target, to overcome space charge issues at injection. As part of the design, we have refined an old proposal to use a RFQ to axially inject bunched H2(+) ions into the driver cyclotron. This method has several advantages over a classical low energy beam transport (LEBT) design: (1) The bunching efficiency is higher than for the previously considered two-gap buncher and thus the overall injection efficiency is higher. This relaxes the constraints on the H2(+) current required from the ion source. (2) The overall length of the LEBT can be reduced. (3) The RFQ can also accelerate the ions. This enables the ion source platform high voltage to be reduced from 70 kV to 15 kV, making underground installation easier. We are presenting the preliminary RFQ design parameters and first beam dynamics simulations from the ion source to the spiral inflector entrance.
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http://dx.doi.org/10.1063/1.4935753 | DOI Listing |
QRB Discov
December 2024
Department of Chemistry, University of Oslo, NO-0315 Oslo, Norway.
Despite major efforts toward its eradication, cholera remains a major health threat and economic burden in many low- and middle-income countries. Between outbreaks, the bacterium responsible for the disease, , survives in aquatic environmental reservoirs, where it commonly forms biofilms, for example, on zooplankton. -acetyl glucosamine-binding protein A (GbpA) is an adhesin that binds to the chitinaceous surface of zooplankton and breaks its dense crystalline packing thanks to its lytic polysaccharide monooxygenase (LPMO) activity, which provides with nutrients.
View Article and Find Full Text PDFResearch (Wash D C)
January 2025
School of Physics & Wuhan National Laboratory for Optoelectronics (WNLO), Huazhong University of Science and Technology (HUST), Wuhan 430074, China.
After years of research and development, flexible sensors are gradually evolving from the traditional "electronic" paradigm to the "ionic" dimension. Smart flexible sensors derived from the concept of ion transport are gradually emerging in the flexible electronics. In particular, ionic hydrogels have increasingly become the focus of research on flexible sensors as a result of their tunable conductivity, flexibility, biocompatibility, and self-healable capabilities.
View Article and Find Full Text PDFLuminescence
January 2025
School of Materials Science and Engineering, Beihang University, Beijing, China.
Mercury ions (Hg) seriously harm the central nervous system of humans, leading to brain damage and even heart failure and death. Therefore, effective detection of Hg in water quality has become an urgent research field. It is very important to develop economically efficient fluorescent sensors to achieve rapid and sensitive detection of Hg.
View Article and Find Full Text PDFJ Chromatogr A
January 2025
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, PR China. Electronic address:
Evodiamine, a chiral quinazoline alkaloid in the traditional Chinese medicine Evodiae fructus, exhibited efficacy for CNS diseases. In this study, the pure enantiomers of evodiamine were prepared in large quantities via chemical resolution. Their structures were elucidated by MS, NMR and ECD.
View Article and Find Full Text PDFEnviron Sci Process Impacts
January 2025
Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, Parsons Laboratory, 15 Vassar Street, Cambridge, Massachusetts 02139, USA.
The high salinity and organic content in oil and gas wastewaters can cause ion suppression during liquid chromatography mass spectrometry (LC/MS) analysis, diminishing the sensitivity and accuracy of measurements in available methods. This suppression is severe for low molecular weight organic compounds such as ethanolamines (, monoethanolamine (MEA), diethanolamine (DEA), triethanolamine (TEA), -methyldiethanolamine (MDEA), and ,-ethyldiethanolamine (EDEA)). Here, we deployed solid phase extraction (SPE), mixed-mode LC, triple quadrupole MS with positive electrospray ionization (ESI), and a suite of stable isotope standards (, one per target compound) to correct for ion suppression by salts and organic matter, SPE losses, and instrument variability.
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