IsoDAR (Isotope Decay-At-Rest) is a novel experiment designed to measure neutrino oscillations through ν̄(e) disappearance, thus providing a definitive search for sterile neutrinos. In order to generate the necessary anti-neutrino flux, a high intensity primary proton beam is needed. In IsoDAR, H2(+) is accelerated and is stripped into protons just before the target, to overcome space charge issues at injection. As part of the design, we have refined an old proposal to use a RFQ to axially inject bunched H2(+) ions into the driver cyclotron. This method has several advantages over a classical low energy beam transport (LEBT) design: (1) The bunching efficiency is higher than for the previously considered two-gap buncher and thus the overall injection efficiency is higher. This relaxes the constraints on the H2(+) current required from the ion source. (2) The overall length of the LEBT can be reduced. (3) The RFQ can also accelerate the ions. This enables the ion source platform high voltage to be reduced from 70 kV to 15 kV, making underground installation easier. We are presenting the preliminary RFQ design parameters and first beam dynamics simulations from the ion source to the spiral inflector entrance.
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Microbiol Resour Announc
January 2025
Department of Microbiology & Immunology, University of Michigan, Ann Arbor, Michigan, USA.
mpactR automates pre-processing of liquid chromatography-tandem mass spectrometry (LC-MS/MS) data from microbiological samples to correct mispicked peaks, resolve inter-sample variation in abundance across technical replicates, account for in-source ion fragmentation, and remove background noise to yield high-quality mass spectrometry features. The package is available through CRAN and GitHub.
View Article and Find Full Text PDFEnviron Health Perspect
January 2025
Silent Spring Institute, Newton, Massachusetts, USA.
Background: Unregulated contaminants in drinking water, such as per- and polyfluoroalkyl substances (PFAS), can contribute to cumulative health risks, particularly in overburdened and less-advantaged communities. To our knowledge, there has been no nationwide assessment of socioeconomic disparities in exposures to unregulated contaminants in drinking water.
Objective: The goals of this study were to identify determinants of unregulated contaminant detection among US public water systems (PWSs) and evaluate disparities related to race, ethnicity, and socioeconomic status.
QRB Discov
December 2024
Department of Chemistry, University of Oslo, NO-0315 Oslo, Norway.
Despite major efforts toward its eradication, cholera remains a major health threat and economic burden in many low- and middle-income countries. Between outbreaks, the bacterium responsible for the disease, , survives in aquatic environmental reservoirs, where it commonly forms biofilms, for example, on zooplankton. -acetyl glucosamine-binding protein A (GbpA) is an adhesin that binds to the chitinaceous surface of zooplankton and breaks its dense crystalline packing thanks to its lytic polysaccharide monooxygenase (LPMO) activity, which provides with nutrients.
View Article and Find Full Text PDFResearch (Wash D C)
January 2025
School of Physics & Wuhan National Laboratory for Optoelectronics (WNLO), Huazhong University of Science and Technology (HUST), Wuhan 430074, China.
After years of research and development, flexible sensors are gradually evolving from the traditional "electronic" paradigm to the "ionic" dimension. Smart flexible sensors derived from the concept of ion transport are gradually emerging in the flexible electronics. In particular, ionic hydrogels have increasingly become the focus of research on flexible sensors as a result of their tunable conductivity, flexibility, biocompatibility, and self-healable capabilities.
View Article and Find Full Text PDFLuminescence
January 2025
School of Materials Science and Engineering, Beihang University, Beijing, China.
Mercury ions (Hg) seriously harm the central nervous system of humans, leading to brain damage and even heart failure and death. Therefore, effective detection of Hg in water quality has become an urgent research field. It is very important to develop economically efficient fluorescent sensors to achieve rapid and sensitive detection of Hg.
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