Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Molecular and immune landscape of tumours in geriatric patients with non-small cell lung cancer, melanoma and renal cell carcinoma.
BMJ Oncol
January 2025
Department of Medicine, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.
Objective: Cancer patients aged ≥80 years present unique characteristics affecting response to immune checkpoint inhibitors (ICIs), with unidentified molecular differences. This study aimed to explore potential biomarkers of response to ICI in patients ≥80 years.
Methods And Analysis: We analysed tumour samples (n=24 123) from patients ≥80 (versus<80) with non-small cell lung cancer (NSCLC), melanoma (MEL), and renal cell cancer (RCC).
Silver nanoparticle-induced antimicrobial resistance in Pseudomonas aeruginosa and Salmonella spp. isolates from an urban lake.
Environ Pollut
January 2025
Department of Environmental Sciences, Southern Illinois University Edwardsville, 44 Circle Drive SW 2145, PO Box 1099, Edwardsville, IL 62026. Electronic address:
The antimicrobial properties and widespread incorporation of silver nanoparticles (AgNPs) into consumer products have raised concerns about their potential impact on public health and the environment. This study examined citrate-coated and uncoated AgNPs' antimicrobial effects on microbial growth and their potential to induce antimicrobial resistance (AMR) in the natural environment. We isolated Pseudomonas aeruginosa and Salmonella spp.
View Article and Find Full Text PDFN-Heterocyclic Carbene Deposition on a Copper Powder Surface Using Mechanochemistry.
ACS Appl Mater Interfaces
January 2025
Department of Chemistry, McGill University, Montréal, Québec H3A 0G4, Canada.
Metal powders are crucial precursors for manufacturing surfaces through thermal spraying, cold spraying, and 3D printing methods. However, surface oxidation of these precursors poses a challenge to the coherence of the metallic materials during manufacturing processes. Herein, we introduce a method for surface modification of copper powder with N-heterocyclic carbenes (NHCs) using mechanochemistry to mitigate surface oxidation.
View Article and Find Full Text PDFDual miRNAs Imaging Platform Based on HRCA-Cas12a by Replacing PAM with Bubble to Reduce False Positive.
Anal Chem
January 2025
Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
Detection and imaging of dual miRNAs based on AND logic gates can improve the accuracy of the early diagnosis of disease. However, a single target may lead to false positive. Hence, this work rationally integrates hyperbranched rolling circle amplification (HRCA) with Cas12a by replacing the PAM sequence with a bubble to sensitively detect and image miRNA-10b and miRNA-21 based on the AND logic gate.
View Article and Find Full Text PDFThe urinary eccDNA landscape in prostate cancer reveals associations with genome instability and vital roles in cancer progression.
J Adv Res
January 2025
Department of Urology, Center for Regeneration and Aging, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu 322000 China. Electronic address:
Introduction: Extrachromosomal circular DNA (eccDNA) plays significant roles in cancer progression and prognosis. However, it remains unclear whether cell-free eccDNA, considered more stable than linear DNA, possesses cancer-specific genomic features. Furthermore, the biogenesis and function of eccDNAs are not yet fully understood.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!