An innovative microneedle (MN)-based cell therapy is developed for glucose-responsive regulation of the insulin secretion from exogenous pancreatic β-cells without implantation. One MN patch can quickly reduce the blood-sugar levels (BGLs) of chemically induced type-1 diabetic mice and stabilize BGLs at a reduced level for over 10 h.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998837 | PMC |
| http://dx.doi.org/10.1002/adma.201506025 | DOI Listing |
Publication Analysis
Top Keywords
microneedles integrated
4
integrated pancreatic
4
pancreatic cells
4
cells synthetic
4
synthetic glucose-signal
4
glucose-signal amplifiers
4
amplifiers smart
4
smart insulin
4
insulin delivery
4
delivery innovative
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!