Scutellarein (2), which is an important in vivo metabolite of scutellarin (1), was synthesized from 3,4,5-trimethoxyphenol (3) in high yield in four steps. This strategy relies on acetylation, aldolization, cyclization and hydrolysis reactions, respectively.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272953 | PMC |
| http://dx.doi.org/10.3390/molecules21030263 | DOI Listing |
Publication Analysis
Top Keywords
scutellarein vivo
8
vivo metabolite
8
metabolite scutellarin
8
efficient chemical
4
chemical synthesis
4
synthesis scutellarein
4
scutellarin scutellarein
4
scutellarin synthesized
4
synthesized 345-trimethoxyphenol
4
345-trimethoxyphenol high
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!