Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Introduction: Clinical studies have shown the usefulness of antimicrobial photodynamic therapy (aPDT) as an adjunctive in periodontal therapy. These studies did not utilize indocyanine green (ICG) as a recently introduced photosensitizer. The aim of this study was to perform a full-mouth double-blind randomized controlled clinical study to test the efficacy of adjunctive aPDT with ICG compared with scaling and root planing (SRP) alone in chronic periodontitis treatment.
Materials And Methods: Fifty patients were selected for this study. All patients received SRP. Then, each patient was randomly assigned to either the test group (aPDT+SRP) or the control group (SRP). aPDT was performed with a diode laser (wavelength: 810nm, power: 200mW) and ICG as photosensitizer. The adjunctive procedure was repeated after 7, 17 and 27 days. The clinical parameters including bleeding on probing (BOP), clinical attachment loss (CAL), plaque index (PI), probing pocket depth (PPD), full mouth plaque score (FMPS) and full mouth bleeding score (FMBS) were measured at baseline and after 1 and 3 months.
Results: There were no significant differences between two groups at baseline. BOP, PPD and FMBS showed significant improvements in the test group (P≤0.001). In terms of PI, FMPS and CAL, no significant differences were observed between both groups (P≥0.05).
Conclusion: aPDT as an adjunctive approach yielded complete resolution of inflammation and significant reduction in periodontal pocket depth. However, aPDT had no additional advantages in clinical attachment gain and plaque score.
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Source |
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http://dx.doi.org/10.1016/j.pdpdt.2016.02.007 | DOI Listing |
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