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Clinicopathologic Study of 28 Cases of Tubulocystic Renal Cell Carcinoma: Is It Time to Reclassify It as a Tubulocystic Renal Cell Tumor?
Cureus
November 2024
Pathology, University of Southern California Keck School of Medicine, Los Angeles, USA.
Tubulocystic renal cell carcinoma (TC-RCC) is uncommon and is defined by exclusive tubulocystic growth. Its clinicopathology is still evolving. Twenty-eight cases of so-defined TC-RCC were studied for clinicopathology as well as, in some cases, immunohistochemistry.
View Article and Find Full Text PDFPseudoinvasion and squamous metaplasia/morules in colorectal adenomatous polyp: a case report and literature review.
Diagn Pathol
September 2024
Department of Pathology, Mudanjiang Medical University Affiliated Hongqi Hospital, No.5 Tongxiang Road, Aimin District, Mudanjiang, Heilongjiang, 157011, China.
Background: Submucosal pseudoinvasion and squamous metaplasia (SM) are incidental and special morphological findings in colorectal adenomas, and both can mimic invasive carcinoma. The coexistence of these two findings further increases the risk of misdiagnosis, posing a great diagnostic challenge to pathologists. From 1979 to 2022, only 8 cases have been reported, which was extremely rare.
View Article and Find Full Text PDFImaging of colorectal adenomas with pseudoinvasion and malignant polyps using two-photon excitation microscopy.
Front Oncol
June 2024
Pathology Department, University of Medicine and Pharmacy, Carol Davila', Bucharest, Romania.
Introduction: Although the incidence and mortality rates of colorectal cancer exhibit significant variability, it remains one of the most prevalent cancers worldwide. Endeavors to prevent colorectal cancer development focus on detecting precursor lesions during colonoscopy. The diagnosis of endoscopically resected polyps relies on hematoxylin and eosin staining examination.
View Article and Find Full Text PDFPathologic significance of peribiliary capillary plexus in gallbladder neoplasm.
Hum Pathol
April 2024
Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan.
Aims: Significance of peribiliary capillary plexus (PCP) in gallbladder neoplasms remains unclear. Aims are to characterize high-grade biliary intraepithelial neoplasm (BilIN), pyloric gland adenoma (PGA), and intracholecystic papillary neoplasm (ICPN), precursors of gallbladder carcinoma, and to differentiate invasive carcinoma from pseudo-invasive lesions in gallbladder walls, referring to PCP.
Materials And Methods: High-grade BilIN (38 cases), PGA (5 cases), and ICPN (25 cases) were examined using capillary immunostaining.
Recognition of pseudoinvasion in colorectal adenoma using spatial glycomics.
Front Med (Lausanne)
January 2024
Department of Pathology, Leiden University Medical Center, Leiden, Netherlands.
Pseudoinvasion (PI) is a benign lesion in which cancer is mimicked in the colon by misplacement of dysplastic glands in the submucosa. Although there are morphological clues, the discrimination of PI from true invasion can be a challenge during pathological evaluation of colon adenomas. Both overdiagnosis and underdiagnosis can result in inadequate clinical decisions.
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