Altogether 100 children suffering from insulin-dependent diabetes mellitus were examined. Analysis of insulin requirement was performed in children with the first disease manifestation and in those with varying disease standing with regard to the type of insulin preparations used. According to the clinical observations, mono-component insulin preparations turned out absolutely superior in the attainment of diabetic process compensation in children with a comparatively low insulin requirement in the course of the treatment of the first disease manifestation and insulin requirement appreciably rose with the increase of the disease standing or superaddition of intercurrent diseases.

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