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| http://dx.doi.org/10.11604/pamj.2015.22.178.7435 | DOI Listing |
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Ubiquitin-Associated Protein 1 (UBAP1) Gene Mutation in a 36-Year-Old Filipino Male With Spastic Paraplegia: A Case Report.
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January 2025
Department of Internal Medicine, Section of Neurology, Chong Hua Hospital, Cebu, PHL.
Hereditary spastic paraplegia (HSP) is a rare neurodegenerative disease caused by retrograde degeneration of the corticospinal tract and posterior columns, which presents with progressive bilateral leg weakness and spasticity. HSP is inherited in an autosomal dominant pattern involving over 80 causative genes. The recently identified causative gene is the ubiquitin-associated protein 1 ()gene, which is associated with juvenile-onset pure spastic paraplegia-80 (SPG80).
View Article and Find Full Text PDFPrevalence of High Frequency Noise-Induced Hearing Loss Among Medical Students Using Personalized Listening Devices.
J Clin Med
December 2024
Department of Otorhinolaryngology, Head and Neck Surgery, Bhaarath Medical College, Chennai 600073, Tamil Nadu, India.
The misuse of personalized listening devices (PLDs) resulting in noise-induced hearing loss (NIHL) has become a public health concern, especially among youths, including medical students. The occupational use of PLDs that produce high-intensity sounds amplifies the danger of cochlear deterioration and high-frequency NIHL especially when used in noisy environments. This study aims to evaluate the incidence and trends of NIHL among medical students using PLDs.
View Article and Find Full Text PDFDegree of Preoperative Bilateral Hearing Affects Patient-Reported Outcome in Primary Stapedotomy.
Otol Neurotol
January 2025
Department of Otorhinolaryngology, Head, and Neck Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Article Synopsis
- The study examines how unilateral versus bilateral hearing impairments affect patient satisfaction and hearing outcomes after stapedotomy surgery.
- Over 90% of patients reported hearing improvements post-surgery, but those with unilateral impairment had lower satisfaction compared to those with bilateral impairments.
- Tinnitus was more prevalent in patients with unilateral hearing issues, indicating additional challenges they faced after the procedure.
The biomechanical effects of treating double-segment lumbar degenerative diseases with unilateral fixation through interlaminar fenestration interbody fusion surgery: a three-dimensional finite element study.
BMC Musculoskelet Disord
January 2025
Orthopedics, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Background: Transforaminal lumbar interbody fusion (TLIF) surgery has become increasingly popular in the surgical treatment of lumbar degenerative diseases. The optimal structure for stable double-segment fixation remains unclear.
Objective: To compare the biomechanical changes of unilateral fixation versus bilateral fixation in patients with lumbar degeneration undergoing double-segment TLIF surgery, and to explore the stability and feasibility of unilateral double-segment fixation.
Lesion correlates of impaired acoustic-phonetic perception after unilateral left hemisphere stroke.
Brain
January 2025
Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Acoustic-phonetic perception refers to the ability to perceive and discriminate between speech sounds. Acquired impairment of acoustic-phonetic perception is known historically as "pure word deafness" and typically follows bilateral lesions of the cortical auditory system. The extent to which this deficit occurs after unilateral left hemisphere damage and the critical left hemisphere areas involved are not well defined.
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